Results 71 to 80 of about 65,332 (236)

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Neupert, Walter, Pfaller, Rupert, Pfanner, Nikolaus, Rassow, Joachim, Steger, Heinrich F.   +4 more
core  

The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress

The FEBS Journal, EarlyView.
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian, Annika Nutz, Katja Hansen, Lea Bertgen, Mirita Franz‐Wachtel, Boris Macek, Johannes M. Herrmann, Doron Rapaport   +7 more
wiley   +1 more source

Maisema värillisenä kaupunkipienoismallina

Ennen ja Nyt: Historian Tietosanomat, 2022
Tämä artikkeli käsittelee kaupunkihistoriallisten pienoismallien värillisyyttä. Artikkelissa tarkastelen neljää alueellisen vastuumuseon perusnäyttelyssä esillä olevaa kaupunkipienoismallia.
Susanna Siro
doaj   +1 more source

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, Neupert, Walter, Schwaiger, Martin   +2 more
core   +3 more sources

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]

, 2013
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
A Keller, A Kemp Jr, A Shevchenko, AA Starkov, AL Goldstein, Andrea M. Hunt, B Cooper, B Guerin, B Hoffmann, B Kucejova, Beata Torocsik, C Chinopoulos, C Chinopoulos, C Janke, C Konrad, C Konrad, Christos Chinopoulos, CP Smith, Cynthia L. David, D De Stefani, DJ Pagliarini, F Jiang, G Arselin, G Brandolin, G Szabadkai, G Woldegiorgis, George Tsaprailis, GJ Lauquin, H Aquila, I Amigo, J Clegg, J Laco, J Traba, J Traba, JA Reynolds, JE Kokoszka, Jeffrey L. Brodsky, JJ Lemasters, JK Eng, JM Baughman, K Beyer, Karoly Vekey, KE Kwast, Lilla Turiak, M Bonora, M Klingenberg, M Rak, M Rey, MA Menze, Monika Wysocka-Kapcinska, NL Andon, NN Zheleznova, O Ozohanics, PJ Henderson, R Craig, R Kramer, R Parvin, RA Haworth, RD Gietz, RK Emaus, Roza Kucharczyk, S Cavero, S Manon, S Uribe, SC Hand, T Hamazaki, TM Rickey, UK Laemmli, V Giorgio, Vera Adam-Vizi, WJ Qian, XJ Chen   +71 more
core   +4 more sources

Anti‐cancer drugs targeting the NADH‐binding site of VDAC rewire channel electrophysiology and partially suppress cation selectivity

The FEBS Journal, EarlyView.
VA molecules alter VDAC1 gating by increasing anion flow and reducing cation permeability. In cancer cells, which rely on ER‐mitochondria Ca2+ transfer and overexpress VDAC1, this imbalance triggers bioenergetic stress, ROS buildup, and mitochondrial collapse, leading to cell death.
Stefano Conti‐Nibali, Giuseppe Battiato, Salvatore Antonio Maria Cubisino, Cristina Arrigoni, Marco Lolicato, Simona Reina, Vito De Pinto   +6 more
wiley   +1 more source

Large-scale prediction of outer-membrane multiheme cytochromes uncovers hidden diversity of electroactive bacteria and underlying pathways

Frontiers in Microbiology
Multi-heme cytochromes (MHCs), together with accessory proteins like porins and periplasmic cytochromes, enable microbes to transport electrons between the cytoplasmic membrane and extracellular substrates (e.g., minerals, electrodes, other cells ...
Arkadiy I. Garber, Kenneth H. Nealson, Nancy Merino   +2 more
doaj   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, EarlyView.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source

Thermomechanical Response of a Representative Porin for Biomimetics [PDF]

ACS Omega, 2018
The thermomechanical response of Omp2a, a representative porin used for the fabrication of smart biomimetic nanomembranes, has been characterized using microcantilever technology and compared with standard proteins. For this purpose, thermally induced transitions involving the conversion of stable trimers to bigger aggregates, local reorganizations ...
Lopes Rodrigues, Maximilien, Puiggalí Jou, Anna, Martí Ballesté, Didac, Valle Mendoza, Luis Javier del, Michaux, Catherine Anne Gisèle, Perpète, Eric A., Alemán Llansó, Carlos   +6 more
openaire   +5 more sources