Results 91 to 100 of about 28,145 (267)
Single or in combination antimicrobial resistance mechanisms of Klebsiella pneumoniae contribute to varied susceptibility to different carbapenems. [PDF]
Resistance to carbapenems has been documented by the production of carbapenemase or the loss of porins combined with extended-spectrum β-lactamases or AmpC β-lactamases.
Yu-Kuo Tsai +4 more
doaj +1 more source
How Salmonella Works Under Osmotic and Desiccation Stresses
ABSTRACT Salmonella remains one of the leading threats in foods with reduced water activity, where it can survive for long periods and cause outbreaks. Its persistence stems from a wide array of adaptive strategies shaped by the selective pressures imposed by low‐moisture foods.
Mayara Messias Oliveira +2 more
wiley +1 more source
Anti-infectives in Drug Delivery-Overcoming the Gram-Negative Bacterial Cell Envelope. [PDF]
Infectious diseases are becoming a major menace to the state of health worldwide, with difficulties in effective treatment especially of nosocomial infections caused by Gram-negative bacteria being increasingly reported.
A Davin-Regli +76 more
core +2 more sources
We developed a systematic workflow to identify genes responsible for 3‐HP import by combining a genomic library with a fluorescent biosensor. Deleting the identified import‐related genes reduced product re‐uptake, successfully increasing 3‐HP titers by 21% and providing a new strategy for optimising microbial production platforms.
Seungjin Kim +4 more
wiley +1 more source
The Role of Transport Mechanisms in Mycobacterium Tuberculosis Drug Resistance and Tolerance
In the fight against tuberculosis, cell wall permeation of chemotherapeutic agents remains a critical but largely unsolved question. Here we review the major mechanisms of small molecule penetration into and efflux from Mycobacterium tuberculosis and ...
Jansy Passiflora Sarathy +2 more
doaj +1 more source
In the environment, bacteria sense aromatic pollutants, migrate toward them, adapt to toxicity, and deploy specialized uptake and catabolic systems. Genomic plasticity, metabolic versatility and division of labor within populations together aid in the degradation of persistent aromatics, highlights that biodegradation is driven by various eco ...
Prashant S. Phale +2 more
wiley +1 more source
The interplay between membrane permeability alterations and the enzymatic barrier contributes to Klebsiella pneumoniae multidrug resistance. We assessed the specific effect of the efflux levels of the main efflux pumps (AcrAB and OqxAB), alone and ...
Marie-Helene Nicolas-Chanoine +6 more
doaj +1 more source
Strategies for maximizing ATP supply in the microsporidian Encephalitozoon cuniculi: direct binding of mitochondria to the parasitophorous vacuole and clustering of the mitochondrial porin VDAC [PDF]
Microsporidia are obligate intracellular parasites with extremely reduced genomes and a dependence on host-derived ATP. The microsporidium Encephalitozoon cuniculi proliferates within a membranous vacuole and we investigated how the ATP supply is ...
Bhella, David +3 more
core +2 more sources
Voltage gating in porin channels [PDF]
Data from experiments in which porin channels are reconstituted into planar bilayer membranes are reviewed for their relevance to porin channel gating in vivo. Contradictory evidence concerning voltage gating indicates that the different results may stem from the variety of purification techniques employed.
openaire +2 more sources
ABSTRACT Plants can perceive specific elicitors in the oral secretions (OS) of herbivorous insects and respond by increasing their defences. Whether plants can discriminate among similar herbivorous insect species and differentially modulate their defence responses against them is largely unknown.
Wenfeng Ye +4 more
wiley +1 more source

