Results 71 to 80 of about 28,145 (267)

Rhenium Complexes as Antimicrobial Agents

open access: yesHelvetica Chimica Acta, EarlyView.
Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley   +1 more source

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou   +8 more
wiley   +1 more source

Surface expression, single-channel analysis and membrane topology of recombinant Major Outer Membrane Protein [PDF]

open access: yes, 2005
Background Chlamydial bacteria are obligate intracellular pathogens containing a cysteine-rich porin (Major Outer Membrane Protein, MOMP) with important structural and, in many species, immunity-related roles.
McClafferty Heather   +2 more
core   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

open access: yesJournal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira   +3 more
wiley   +1 more source

Teleological cooption of Mycobacterium tuberculosis PE/PPE proteins as porins: Role in molecular immigration and emigration

open access: yesInternational Journal of Medical Microbiology, 2021
Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M.
Aquib Ehtram   +8 more
doaj   +1 more source

Holling Type I versus Holling Type II functional responses in Gram-negative bacteria [PDF]

open access: yes, 2018
We consider how the double-membrane structure of the cell envelope of Gram-negative bacteria affects its functional response, which is the mathematical relationship that expresses how the nutrient uptake flux depends on environmental conditions.
Berg, Hugo van den, Nev, Olga
core   +2 more sources

The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress

open access: yesThe FEBS Journal, EarlyView.
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian   +7 more
wiley   +1 more source

Membrane proteins in the outer mebrane of plastids and mitochondria [PDF]

open access: yes, 2006
Channels of the plastid and mitochondrial outer membranes facilitate the turnover of molecules and ions via these membranes. Although channels have been studied many questions pertaining to the whole diversity of plastid and mitochondrial channels in ...
Ilkavets, Iryna
core  

Role of metal-dependent regulation of ESX-3 secretion in intracellular survival of Mycobacterium tuberculosis [PDF]

open access: yes, 2016
More people die every year from Mycobacterium tuberculosis infection than from infection by any other bacterial pathogen. Type VII secretion systems (T7SS) are used by both environmental and pathogenic mycobacteria to secrete proteins across their ...
Philips, Jennifer A   +5 more
core   +2 more sources

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

open access: yesThe FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna   +5 more
wiley   +1 more source

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