Results 51 to 60 of about 12,287 (215)

Porin from Rhodopseudomonas sphaeroides [PDF]

open access: yesJournal of Bacteriology, 1984
A protein homooligomer was purified from both the cell envelope fractions and the saline extracts of Rhodopseudomonas sphaeroides cells. This oligomer exhibited strong porin activity when reconstituted into proteoliposomes with egg phosphatidylcholine. In the saline extracts of both chemotrophically and phototrophically grown cells, the porin oligomer ...
J, Weckesser, L S, Zalman, H, Nikaido
openaire   +2 more sources

Rational Design of a Synthetic Galliphore for the Diagnostic Nuclear Imaging and Treatment of Bacterial Infections

open access: yesAngewandte Chemie, EarlyView.
KO‐NH2 is a synthetic metallophore that preferentially binds Ga3+ over Fe3+ and is recognized by bacterial transporters. Photocrosslinking identifies CirA and Fiu as key uptake proteins in E. coli. KO‐NH2 enables targeted imaging and treatment of E. coli soft tissue infections.
Phuong Nguyen Tran   +5 more
wiley   +2 more sources

Asymmetric conductivity of engineered porins [PDF]

open access: yesProtein Engineering, Design and Selection, 2002
Positively charged peptide segments of 16 and 18 residues were inserted at a periplasmic turn of the porin from Rhodobacter blasticus in order to form an electric field-dependent plug. The X-ray diffraction analysis of a mutant confirmed that the structure of the porin had remained intact and that the insert was mobile.
Bannwarth, Michael, Schulz, Georg E.
openaire   +3 more sources

Fluoroquinolone-Transition Metal Complexes: A Strategy to Overcome Bacterial Resistance

open access: yesMicroorganisms, 2021
Fluoroquinolones (FQs) are antibiotics widely used in the clinical practice due to their large spectrum of action against Gram-negative and some Gram-positive bacteria.
Mariana Ferreira, Paula Gameiro
doaj   +1 more source

Socialization of Providencia stuartii Enables Resistance to Environmental Insults

open access: yesMicroorganisms, 2022
Providencia stuartii is a highly social pathogen responsible for nosocomial chronic urinary tract infections. The bacterium indeed forms floating communities of cells (FCC) besides and prior-to canonical surface-attached biofilms (SAB).
Julie Lopes   +4 more
doaj   +1 more source

Efflux Pumps and Porins Enhance Bacterial Tolerance to Phenolic Compounds by Inhibiting Hydroxyl Radical Generation

open access: yesMicroorganisms
Phenolic compounds are industrially versatile chemicals that have been successfully produced in microbial cell factories. Unfortunately, most phenolic compounds are highly toxic to cells in specific cellular environments or above a particular ...
Xinyue Sui   +4 more
doaj   +1 more source

Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens

open access: yesVaccines, 2017
Chlamydia is the most common cause of bacterial sexually transmitted infections worldwide. While infections resolve with antibiotic treatment, this is often neglected in women due to frequent asymptomatic infections, leading to disease progression and ...
Guillermo Madico   +3 more
doaj   +1 more source

Penetration through Outer Membrane and Efflux Potential in Pseudomonas aeruginosa of Bulgecin A as an Adjuvant to β-Lactam Antibiotics

open access: yesAntibiotics, 2023
The treatment of infections by Gram-negative bacteria remains a difficult clinical challenge. In the light of the dearth of discovery of novel antibiotics, one strategy that is being explored is the use of adjuvants to enhance antibacterial activities of
Choon Kim   +4 more
doaj   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

open access: yesAdvanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu   +8 more
wiley   +1 more source

Osmotically-Driven Transport in Carbon Nanotube Porins

open access: yes, 2016
We report the measurements of transport of ions and uncharged species through carbon nanotube (CNT) porinsshort segments of CNTs inserted into a lipid bilayer membrane.
Luis R. Comolli (204466)   +6 more
core   +1 more source

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