Results 41 to 50 of about 12,287 (215)
Antibiotics, 2021 Meropenem/Vaborbactam (MEM-VAB) is a novel carbapenem- β-lactamase inhibitor active against KPC-producing Enterobacteria. Herein, we evaluate the incidence of meropenem/vaborbactam-resistance among KPC-producing K.
Paolo Gaibani +9 more
doaj +1 more source
A mitochondrial porin cDNA predicts the existence of multiple human porins
Journal of Biological Chemistry, 1993 Pores formed in the outer membrane of mitochondria by mitochondrial porin make it permeable to water-soluble metabolites smaller than approximately 5 kDa. We have isolated a full-length cDNA encoding a human porin. This probe detects a single approximately 1.5-kilobase mRNA species on Northern blots, but multiple hybridizing bands on genomic Southern ...
H, Ha +3 more
openaire +2 more sources
Rosette Nanotube Porins as Ion Selective Transporters and Single-Molecule Sensors
Journal of the American Chemical Society, 2020 Rosette nanotubes (RNTs) are a class of materials formed by molecular self-assembly of a fused guanine-cytosine base (G∧C base). An important feature of these self-assembled nanotubes is their precise atomic structure, intriguing for rational design and ...
Prabhat Tripathi +7 more
semanticscholar +1 more source
Multiple facets of bacterial porins [PDF]
FEMS Microbiology Letters, 2001 Porins form channels allowing the transport of molecules across lipid bilayer membranes. Their structure, location and large number on the bacterial surface lend them multiple functions. Porin loops are potential targets for adhesion to other cells and binding of bactericidal compounds to the surface of Gram-negative bacteria.
W, Achouak, T, Heulin, J M, Pagès
openaire +2 more sources
Structural and functional studies of porins from pathogenic bacteria [PDF]
, 2018 Multi-drug resistant bacteria have become a real threat to public health worldwide. Gram-negative bacteria, in particular, have shown high level of antibiotic resistance due to the presence of an additional membrane, known as outer-membrane (OM), that ...
Ferrara, Luana
core +2 more sources
Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae. [PDF]
Structure, 2018 The outer membranes (OM) of many Gram-negative bacteria contain general porins, which form nonspecific, large-diameter channels for the diffusional uptake of small molecules required for cell growth and function. While the porins of Enterobacteriaceae (e.
M. Pathania +6 more
semanticscholar +3 more sources
Angewandte Chemie, EarlyView.Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui +9 more
wiley +2 more sources
Journal of Infection in Developing Countries, 2018 Introduction: Antimicrobial resistant bacterial infections are widespread globally and increases in antimicrobial resistance presents a major threat to public health.
Ashika Singh-Moodley +12 more
doaj +1 more source
SSTAR, a Stand-Alone Easy-To-Use Antimicrobial Resistance Gene Predictor
mSphere, 2016 We present the easy-to-use Sequence Search Tool for Antimicrobial Resistance, SSTAR. It combines a locally executed BLASTN search against a customizable database with an intuitive graphical user interface for identifying antimicrobial resistance (AR ...
Tom J. B. de Man, Brandi M. Limbago
doaj +1 more source
Frontiers in Physiology, 2021 Eukaryotic porin, also known as Voltage-Dependent Anion Channel (VDAC), is the most frequent protein in the outer membrane of mitochondria that are responsible for cellular respiration.
Roland Benz
doaj +1 more source