Results 31 to 40 of about 28,145 (267)
Frontiers in Bioengineering and Biotechnology, 2020 In the last decade, the development of novel programmable cell lytic systems based on different inducible genetic constructs like the holin–endolysin and lysozyme appears as a promising alternative to circumvent the use of costly enzymes and mechanical ...
Ignacio Poblete-Castro +6 more
doaj +1 more source
Evolving strategies for single-celled organisms in multi-nutrient environments [PDF]
, 2015 When micro-organisms are in environments with multiple nutrients, they often preferentially utilise one first. A second is only utilised once the first is exhausted. Such a two-phase growth pattern is known as diauxic growth.
Barnes, David J., Chu, Dominique
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In silico evolution of diauxic growth [PDF]
, 2015 The glucose effect is a well known phenomenon whereby cells, when presented with two different nutrients, show a diauxic growth pattern, i.e. an episode of exponential growth followed by a lag phase of reduced growth followed by a second phase of ...
A Bennett +37 more
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Nature Methods, 2014 Lipid-coated carbon nanotubes can insert themselves spontaneously into lipid bilayers and live-cell membranes.
openaire +2 more sources
The Influence of Permeability through Bacterial Porins in Whole-Cell Compound Accumulation
Antibiotics, 2021 The lack of new drugs for Gram-negative pathogens is a global threat to modern medicine. The complexity of their cell envelope, with an additional outer membrane, hinders internal accumulation and thus, the access of molecules to their targets.
Silvia Acosta-Gutiérrez +2 more
doaj +1 more source
Structural Metrics Predict Site-Specific Evolutionary Rate in Membrane Bound Proteins [PDF]
, 2016 Membrane proteins are involved in many critical biological processes and mutations are linked to various diseases. We examined how the properties of the location of an amino acid residue within the protein structure dictates the rate at which it evolves.
Du, Xuezhen
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Antibiotics, 2021 Meropenem/Vaborbactam (MEM-VAB) is a novel carbapenem- β-lactamase inhibitor active against KPC-producing Enterobacteria. Herein, we evaluate the incidence of meropenem/vaborbactam-resistance among KPC-producing K.
Paolo Gaibani +9 more
doaj +1 more source
Structural analysis of outer membrane beta-stranded porins using B-factor [PDF]
, 2009 Computational and statistical analysis has formed a large component of the biophysical efforts put forth to understand protein structure and function, due to the diversity and complexity of their structure.
Abhishek Kumar, S Krishnaswamy
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Microorganisms, 2021 Salmonella enterica serovar Typhi (S. Typhi) porins, OmpC and OmpF, are potent inducers of the immune response against S. Typhi in mice and humans. Vaccination with porins induces the protection against 500 LD50 of S.
Luis Ontiveros-Padilla +8 more
doaj +1 more source
Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes. [PDF]
, 2012 Synucleinopathies such as Parkinson's disease, multiple system atrophy and dementia with Lewy bodies are characterized by deposition of aggregated α-synuclein.
Bötzel, Kai +5 more
core +2 more sources