Results 11 to 20 of about 28,145 (267)

Quantitative assessment of porin-mediated solute transport in biomimetic membranes [PDF]

open access: yesApplied Microbiology and Biotechnology
Porins govern nutrient uptake and antibiotic influx in Gram-negative bacteria, making their characterization critical for understanding permeability, resistance mechanisms, and structure-function relationships. From a biotechnological point of view, they
Maike Scherer   +5 more
doaj   +2 more sources

Outer membrane permeability of Pseudomonas aeruginosa through β-lactams: new evidence on the role of OprD and OpdP porins in antibiotic resistance [PDF]

open access: yesMicrobiology Spectrum
Gram-negative bacteria are a major concern for public health, particularly due to the continuous rise of antibiotic resistance. A major factor that helps the development of resistance is the outer membrane that is essential since it acts as a strong ...
Francesco Amisano   +7 more
doaj   +2 more sources

Antibiotics and phages drive region-specific diversity of OmpK36 in Klebsiella pneumoniae [PDF]

open access: yesmBio
The Enterobacterales outer membrane is impermeable to many antibiotics, but they can enter the cell via channel proteins, called porins. In Klebsiella pneumoniae, the porin OmpK36 is a major determinant of antibiotic resistance.
Guilhem Royer   +7 more
doaj   +2 more sources

Outer Membrane Porins Contribute to Antimicrobial Resistance in Gram-Negative Bacteria

open access: yesMicroorganisms, 2023
Gram-negative bacteria depend on their cell membranes for survival and environmental adaptation. They contain two membranes, one of which is the outer membrane (OM), which is home to several different outer membrane proteins (Omps).
Gang Zhou   +8 more
doaj   +1 more source

Immunochemical activity of Yersinia pseudotuberculosis ompF and ompC porins evaluated by optical trapping

open access: yesИнфекция и иммунитет, 2022
Introduction. Study of features for interacting antigen-antibody system is of great importance for developing new modern tools for diagnostics and therapy of infectious diseases.
Ilya V. Konyshev   +3 more
doaj   +1 more source

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

open access: yesApplied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +1 more source

Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

open access: yesFrontiers in Immunology, 2020
Immunotherapy has improved the clinical response in melanoma patients, although a relevant percentage of patients still cannot be salvaged. The search for the immune populations that provide the best tumor control and that can be coaxed by immunotherapy ...
Ricardo A. León-Letelier   +12 more
doaj   +1 more source

Roles of the EnvZ/OmpR Two-Component System and Porins in Iron Acquisition in Escherichia coli

open access: yesmBio, 2020
Escherichia coli secretes high-affinity Fe3+ chelators to solubilize and transport chelated Fe3+ via specific outer membrane receptors. In microaerobic and anaerobic growth environments, where the reduced Fe2+ form is predominant, ferrous transport ...
Henri Gerken   +3 more
doaj   +1 more source

The Small RNA NcS25 Regulates Biological Amine-Transporting Outer Membrane Porin BCAL3473 in Burkholderia cenocepacia

open access: yesmSphere, 2023
Regulation of porin expression in bacteria is complex and often involves small-RNA regulators. Several small-RNA regulators have been described for Burkholderia cenocepacia, and this study aimed to characterize the biological role of the conserved small ...
Andrea M. Sass, Tom Coenye
doaj   +1 more source

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