Results 21 to 30 of about 12,287 (215)

Roles of the EnvZ/OmpR Two-Component System and Porins in Iron Acquisition in Escherichia coli

mBio, 2020
Escherichia coli secretes high-affinity Fe3+ chelators to solubilize and transport chelated Fe3+ via specific outer membrane receptors. In microaerobic and anaerobic growth environments, where the reduced Fe2+ form is predominant, ferrous transport ...
Henri Gerken, Phu Vuong, Ketaki Soparkar, Rajeev Misra   +3 more
doaj   +1 more source

Teleological cooption of Mycobacterium tuberculosis PE/PPE proteins as porins: Role in molecular immigration and emigration.

International Journal of Medical Microbiology, 2021
Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M.
Aquib Ehtram, Mohd. Shariq, S. Ali, N. Quadir, J. Sheikh, Faraz Ahmad, Tarina Sharma, N. Ehtesham, S. Hasnain   +8 more
semanticscholar   +1 more source

The Small RNA NcS25 Regulates Biological Amine-Transporting Outer Membrane Porin BCAL3473 in Burkholderia cenocepacia

mSphere, 2023
Regulation of porin expression in bacteria is complex and often involves small-RNA regulators. Several small-RNA regulators have been described for Burkholderia cenocepacia, and this study aimed to characterize the biological role of the conserved small ...
Andrea M. Sass, Tom Coenye
doaj   +1 more source

Antiproliferative effects of porins extracted from Klebsiella pneumoniae on HL-60, NIH/3T3 and Human foreskin fibroblast cell (HFFC) lines measured by ELISA method

مجلة مركز بحوث التقنيات الاحيائية, 2010
Approximately, 50% of the dry mass of the outer membrane of gram-negative bacteria consists of proteins, and more than 20 immunochemically distinct proteins (termed outer membrane proteins [OMPs]) have been identified.
Amir H. Al–Shammary, Essam F. Al-Jumaily, Nidhal Abdulmohymen   +2 more
doaj   +3 more sources

Genomic Characterization of Mutli-Drug Resistant Pseudomonas aeruginosa Clinical Isolates: Evaluation and Determination of Ceftolozane/Tazobactam Activity and Resistance Mechanisms

Frontiers in Cellular and Infection Microbiology, 2022
Resistance to ceftolozane/tazobactam (C/T) in Pseudomonas aeruginosa is a health concern. In this study, we conducted a whole-genome-based molecular characterization to correlate resistance patterns and β-lactamases with C/T resistance among multi-drug ...
Ibrahim Bitar, Ibrahim Bitar, Tamara Salloum, Georgi Merhi, Jaroslav Hrabak, Jaroslav Hrabak, George F. Araj, Sima Tokajian   +7 more
doaj   +1 more source

Permeability Through Bacterial Porins Dictates Whole Cell Compound Accumulation [PDF]

, 2020
The lack of new drugs for Gram-negative pathogens is a global threat to modern medicine. The complexity of their cell envelope, with an additional outer membrane, hinders ...
Igor, Bodrenko, Silvia, Acosta Gutiérrez, Matteo, Ceccarelli   +2 more
core   +2 more sources

High-Level Carbapenem Resistance among OXA-48-Producing Klebsiellapneumoniae with Functional OmpK36 Alterations: Maintenance of Ceftazidime/Avibactam Susceptibility

Antibiotics, 2021
The aim of this work was to analyze outer membrane porin-encoding genes (ompK35 and ompK36) in a collection of OXA-48 producing Klebsiella pneumoniae, to assess the effect of porin alterations on the susceptibility to ceftazidime/avibactam, and to ...
Pilar Lumbreras-Iglesias, María Rosario Rodicio, Pablo Valledor, Tomás Suárez-Zarracina, Javier Fernández   +4 more
doaj   +1 more source

Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli [PDF]

, 2011
This work is also partially supported by BBSRC and the Scottish Funding Council (through SULSA)Antibiotic-resistant bacteria, particularly Gram negative species, present significant health care challenges.
H. Lou, M. Chen, Susan S Black, Beis Konstantinos, Bayley Hagan, Matteo Ceccarelli, Beis, Konstantinos, Bushell, SR, Ian R Booth, Victoria A. Bamford, A. Low, Alison S Low, Bamford Victoria A., I. R. Booth, Ceccarelli Matteo, Bushell, Simon R, Ceccarelli, Matteo, Ceccarelli, M, V. A. Bamford, J. H. Naismith, James H. Naismith, James H Naismith, Booth, Ian R, Bamford, Victoria A., Naismith James H., Lou Hubing, Booth Ian R., Low, AS, Black, Susan S, Low, Alison S, Naismith, James H, Tivadar Mach, S. S. Black, Naismith, JH, H. Bayley, Low, Alison S., Mach, T, Black, Susan S., Chen, M, Bushell Simon R., Simon R. Bushell, Susan S. Black, Low Alison S., Mach Tivadar, Beis, K, Hagan Bayley, Bushell, Simon R., Min Chen, Bamford, Victoria A, Bamford, VA, K. Beis, Lou, H, Ian R. Booth, S. R. Bushell, Mach, Tivadar, Konstantinos Beis, Lou, Hubing, Booth, IR, Black Susan S., Bayley, Hagan, Alison S. Low, Naismith, James H., T. Mach, Chen Min, Booth, Ian R., Simon R Bushell, Bayley, H, Chen, Min, Victoria A Bamford, Black, SS, Hubing Lou   +70 more
core   +1 more source

Molecular genetic characteristics of the carbapenem resistant Klebsiella pneumoniae KP254 strain as a representative of the highly virulent strain evolutionary branch

Инфекция и иммунитет, 2021
Here we provide molecular and genetic characteristics of the Klebsiella pneumoniae KP254 clinical strain belonging to clonal group 23 based on the genome-wide sequencing data.
A. E. Alekseeva, N. F. Brusnigina, N. A. Gordinskaya   +2 more
doaj   +1 more source

Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]

, 2007
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Philippar, Katrin, Soll, Jürgen, Duy, Daniela   +2 more
core   +1 more source