Results 71 to 80 of about 6,920,570 (282)

Civility behaviour training programme and its influence on staff nurse organisational citizenship: a quasi-experimental study

Frontiers in Public Health
BackgroundThis study aimed to assess the influence of a civility behaviour training programme on organisational citizenship among nurses in the workplace and to explore various predictors of nurses’ knowledge, workplace civility behaviour, and ...
Eman Mohamed El-Shahat, Hemat Abdelazem Mostafa, Mona Mostafa Shazly   +2 more
doaj   +1 more source

Leadership empowering behaviour, psychological empowerment, organisational citizenship behaviours and turnover intention in a manufacturing division

SA Journal of Industrial Psychology, 2015
Orientation: Employees’ perceptions of their leaders’ behaviour play a role in creating empowering environments where employees are willing to do more than what is expected, with retention of employees as a result. Research purpose: The aim of this study
Janie Bester, Marius W. Stander, Llewellyn E. van Zyl   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Organisational factors influencing the diffusion of process innovations from manufacturing to health services settings

, 2010
Background: This paper presents an Organisational Behaviour perspective of organisational factors influencing diffusion of innovation in a medium-sized tertiary public hospital.
Fitzgerald, Anneke (R10311), Sloan, Terrence R. (R8595), Dadich, Ann M. (R10177), Kobilski, Sacha, Hayes, Kathryn J. (R12313), Eljiz, Kathy (R13851)   +5 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Innovative Work Behaviour, Emotional Intelligence, Creativity, and Organisational Climate in High Schools

Organizacijų Vadyba: Sisteminiai Tyrimai
Innovations are one of the driving forces leading towards sustainable future, and schools represent a space where young people learn to use and create innovations.
Škudienė Vida, Augutytė-Kvedaravičienė Ieva, Ramanauskienė Ieva Marija, Pociūtė Rolanda   +3 more
doaj   +1 more source

Workplace flourishing: Measurement, antecedents and outcomes

SA Journal of Industrial Psychology, 2019
Orientation: The continuous growth of employee attrition, especially within the highly skilled talent pool, is becoming increasingly problematic.
Kleinjan Redelinghuys, Sebastiaan Rothmann, Elrie Botha   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source