Results 41 to 50 of about 5,230,574 (296)

Identification of Genes under Positive Selection Reveals Differences in Evolutionary Adaptation between Brown-Algal Species

Frontiers in Plant Science, 2017
Brown algae are an important taxonomic group in coastal ecosystems. The model brown algal species Ectocarpus siliculosus and Saccharina japonica are closely related lineages.
Linhong Teng, Xiao Fan, Dong Xu, Xiaowen Zhang, Thomas Mock, Naihao Ye, Naihao Ye   +6 more
doaj   +1 more source

High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer

Frontiers in Microbiology, 2020
Human papillomavirus type 16 (HPV16) is the most common HPV genotype found in invasive cervical cancer (ICC). Recent comprehensive genomics studies of HPV16 have revealed that a large number of minor nucleotide variations in the viral genome are present ...
Yusuke Hirose, Mayuko Yamaguchi-Naka, Mamiko Onuki, Yuri Tenjimbayashi, Nobutaka Tasaka, Toyomi Satoh, Kohsei Tanaka, Kohsei Tanaka, Takashi Iwata, Akihiko Sekizawa, Koji Matsumoto, Iwao Kukimoto   +11 more
doaj   +1 more source

Functional conservation and divergence in plant-specific GRF gene family revealed by sequences and expression analysis

Open Life Sciences, 2022
Unique to plants, growth regulatory factors (GRFs) play important roles in plant growth and reproduction. This study investigated the evolutionary and functional characteristics associated with plant growth. Using genome-wide analysis of 15 plant species,
Meng Lingyan, Li Xiaomeng, Hou Yue, Li Yaxuan, Hu Yingkao   +4 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Comparative Genomics Reveals Accelerated Evolution of Fright Reaction Genes in Ostariophysan Fishes

Frontiers in Genetics, 2019
The ostariophysian fishes are the most species-rich clade in freshwaters. This diversification has been suggested to be associated with the fright reaction presented in most ostariophysians.
Liandong Yang, Haifeng Jiang, Haifeng Jiang, Juan Chen, Juan Chen, Yi Lei, Yi Lei, Ning Sun, Ning Sun, Wenqi Lv, Wenqi Lv, Thomas J. Near, Shunping He, Shunping He, Shunping He   +14 more
doaj   +1 more source

Evidence of hard‐selective sweeps suggests independent adaptation to insecticides in Colorado potato beetle (Coleoptera: Chrysomelidae) populations

Evolutionary Applications, 2022
Pesticide resistance provides one of the best examples of rapid evolution to environmental change. The Colorado potato beetle (CPB) has a long and noteworthy history as a super‐pest due to its ability to repeatedly develop resistance to novel ...
Zachary P. Cohen, Yolanda H. Chen, Russell Groves, Sean D. Schoville   +3 more
doaj   +1 more source

Genomic changes underpinning the emergence of a successful Mycobacterium tuberculosis Latin American and Mediterranean clonal complex

Frontiers in Microbiology, 2023
IntroductionThe Latin American and Mediterranean sublineage (L4.3/LAM) is the most common generalist sublineage of Mycobacterium tuberculosis lineage 4 (L4), yet certain L4.3/LAM genotypes appear to be confined to particular geographic regions.
Naira Dekhil, Helmi Mardassi
doaj   +1 more source

Optimal securities under adverse selection and moral hazard [PDF]

, 2009
We consider project financing under adverse selection and moral hazard and derive several interesting results. First, we provide an explanation of why good firms issue both debt and underpriced equity (even if the bankruptcy and agency costs of debt are ...
Koufopoulos, Kostas
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice

Frontiers in Immunology, 2019
Xlf/Cernunnos is unique among the core factors of the non-homologous end joining (NHEJ) DNA double strand breaks (DSBs) repair pathway, in the sense that it is not essential for V(D)J recombination in vivo and in vitro.
Benoit Roch, Benoit Roch, Vincent Abramowski, Vincent Abramowski, Julie Chaumeil, Jean-Pierre de Villartay, Jean-Pierre de Villartay   +6 more
doaj   +1 more source