Results 21 to 30 of about 1,927,312 (260)
Frontiers in Ecology and Evolution, 2015 In moths, mate finding strongly rely on the detection of sex pheromones by pheromone receptors. Any modification in the functional properties of these receptors can have a drastic impact on reproduction.
Arthur ede Fouchier +11 more
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T cell self-reactivity during thymic development dictates the timing of positive selection
eLife, 2021 Functional tuning of T cells based on their degree of self-reactivity is established during positive selection in the thymus, although how positive selection differs for thymocytes with relatively low versus high self-reactivity is unclear.
Lydia K Lutes +9 more
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Corruption and positive selection in privatization [PDF]
Research in Economics, 2008 We consider the supply of a public good based on a publicly-owned facility. The Government has a choice between provision in-house and privatizing the facility and then outsourcing the production. In particular, we focus on corruption in the decision to privatize and on its effect on social welfare when there is asymmetric information on the public and
M. Cristina Molinari, Raluca Buia
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Evolution and Structural Analyses of Glossina morsitans (Diptera; Glossinidae) Tetraspanins
Insects, 2014 Tetraspanins are important conserved integral membrane proteins expressed in many organisms. Although there is limited knowledge about the full repertoire, evolution and structural characteristics of individual members in various organisms, data obtained
Edwin K. Murungi +4 more
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Frontiers in Microbiology, 2020 The genomes of plant pathogenic fungi and oomycetes are often exposed to strong positive selection pressure. During speciation, shifts in host range and preference can lead to major adaptive changes.
Mark C. Derbyshire
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Prediction of Genes Related to Positive Selection Using Whole-Genome Resequencing in Three Commercial Pig Breeds [PDF]
Genomics & Informatics, 2015 Selective sweep can cause genetic differentiation across populations, which allows for the identification of possible causative regions/genes underlying important traits.
HyoYoung Kim +6 more
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Viral Interference with Functions of the Cellular Receptor Tyrosine Phosphatase CD45
Viruses, 2015 The receptor tyrosine phosphatase CD45 is expressed on the surface of almost all cells of hematopoietic origin. CD45 functions are central to the development of T cells and determine the threshold at which T and B lymphocytes can become activated.
Nadine Thiel +4 more
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On the logic of positive selection
Immunology, 2006 This is a comment that questions the almost unanimous assumption that the T-cell antigen receptor (TCR) delivers distinctly different signals dependent on the level or duration of occupancy. When the TCR of the thymic precursor (CD4+ CD8+) (referred to here as oT) docks on the major histocompatibility complex-encoded restricting element (referred to
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source