Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus
Since its first isolation in around 2007, the avian-origin H3N2 canine influenza virus (CIV) has become established and continues to circulate in dog populations.
Fucheng Guo +16 more
doaj +1 more source
Phosphatidylinositol 3-kinase improves the efficiency of positive selection [PDF]
We have generated transgenic mice expressing the amino-terminal fragment of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit (p110(ABD)) in thymocytes.
Alberola-Ila, José, Barbee, Susannah D.
core +1 more source
A survey of methods and tools to detect recent and strong positive selection
Positive selection occurs when an allele is favored by natural selection. The frequency of the favored allele increases in the population and due to genetic hitchhiking the neighboring linked variation diminishes, creating so-called selective sweeps ...
Pavlos Pavlidis, Nikolaos Alachiotis
doaj +1 more source
Detection of selection signatures in dairy and beef cattle using high-density genomic information [PDF]
peer-reviewedBackground Artificial selection for economically important traits in cattle is expected to have left distinctive selection signatures on the genome. Access to high-density genotypes facilitates the accurate identification of
Berry, Donagh +4 more
core +3 more sources
Positive selection underlies Faster-Z evolution of gene expression in birds. [PDF]
The elevated rate of evolution for genes on sex chromosomes compared to autosomes (Fast-X or Fast-Z evolution) can result either from positive selection in the heterogametic sex, or from non-adaptive consequences of reduced relative effective population ...
Dean, R +4 more
core +1 more source
Detecting positive selection in the genome
Population geneticists have long sought to understand the contribution of natural selection to molecular evolution. A variety of approaches have been proposed that use population genetics theory to quantify the rate and strength of positive selection ...
Tom R. Booker +2 more
doaj +1 more source
A conditional marker gene allowing both positive and negative selection in plants [PDF]
Selectable markers enable transgenic plants or cells to be identified after transformation. They can be divided into positive and negative markers conferring a selective advantage or disadvantage, respectively.
Erikson, Oskar +2 more
core +1 more source
DNA damage response (DDR) is a complicated network to defend against physical or chemical changes in DNA in all animals. Elevated levels of ultraviolet radiation (UVR) caused DNA damage, which was a reason for the mass extinction that occurred at the ...
Tianzhen Wu +5 more
doaj +1 more source
Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules [PDF]
THE α1 and α2 domains of major histocompatibility complex (MHC) class I molecules function in the binding and presentation of foreign peptides to the T-cell antigen receptor and control both negative and positive selection of the T-cell repertoire ...
AM Norment +30 more
core +1 more source
Population size may shape the accumulation of functional mutations following domestication
Background Population genetics theory predicts an important role of differences in the effective population size (N e ) among species on shaping the accumulation of functional mutations by regulating the selection efficiency.
Jianhai Chen +6 more
doaj +1 more source

