Results 11 to 20 of about 1,927,312 (260)
Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus
Frontiers in Microbiology, 2021 Since its first isolation in around 2007, the avian-origin H3N2 canine influenza virus (CIV) has become established and continues to circulate in dog populations.
Fucheng Guo +16 more
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A survey of methods and tools to detect recent and strong positive selection
Journal of Biological Research - Thessaloniki, 2017 Positive selection occurs when an allele is favored by natural selection. The frequency of the favored allele increases in the population and due to genetic hitchhiking the neighboring linked variation diminishes, creating so-called selective sweeps ...
Pavlos Pavlidis, Nikolaos Alachiotis
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Frontiers in Marine Science, 2023 DNA damage response (DDR) is a complicated network to defend against physical or chemical changes in DNA in all animals. Elevated levels of ultraviolet radiation (UVR) caused DNA damage, which was a reason for the mass extinction that occurred at the ...
Tianzhen Wu +5 more
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Population size may shape the accumulation of functional mutations following domestication
BMC Evolutionary Biology, 2018 Background Population genetics theory predicts an important role of differences in the effective population size (N e ) among species on shaping the accumulation of functional mutations by regulating the selection efficiency.
Jianhai Chen +6 more
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Selective Role of NFATc3 in Positive Selection of Thymocytes [PDF]
The Journal of Immunology, 2007 Abstract The four Ca2+-dependent NFATc proteins are both signal transducers and transcription factors that reside in the cytoplasm until dephosphorylation by calcineurin. Dephosphorylation exposes nuclear import sequences and sends NFATc proteins into the nucleus where they assemble with nuclear partners into NFAT transcription complexes.
Kirsten, Canté-Barrett +2 more
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Positions under Positive Selection--Key for Selectivity and Potency of Scorpion -Toxins [PDF]
Molecular Biology and Evolution, 2009 Alpha-neurotoxins target voltage-gated sodium channels (Na(v)s) and constitute an important component in the venom of Buthidae scorpions. These toxins are short polypeptides highly conserved in sequence and three-dimensional structure, and yet they differ greatly in activity and preference for insect and various mammalian Na(v)s.
Hagar, Weinberger +5 more
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Positive selection on the human genome [PDF]
Human Molecular Genetics, 2004 Positive selection has undoubtedly played a critical role in the evolution of Homo sapiens. Of the many phenotypic traits that define our species--notably the enormous brain, advanced cognitive abilities, complex vocal organs, bipedalism and opposable thumbs--most (if not all) are likely the product of strong positive selection.
Eric J, Vallender, Bruce T, Lahn
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The draft genome of the blood pheasant (Ithaginis cruentus): Phylogeny and high‐altitude adaptation
Ecology and Evolution, 2020 The blood pheasant (Ithaginis cruentus), the only species in the genus Ithaginis, lives in an extremely inhospitable high‐altitude environment, coping with hypoxia and ultraviolet (UV) radiation.
Chuang Zhou +6 more
doaj +1 more source
Selectome: a database of positive selection [PDF]
Nucleic Acids Research, 2009 Genome wide scans have shown that positive selection is relatively frequent at the molecular level. It is of special interest to identify which protein sites and which phylogenetic branches are affected. We present Selectome, a database which provides the results of a rigorous branch-site specific likelihood test for positive selection.
Estelle Proux-Wéra +3 more
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