Identification of a Candidate IgE-Binding Maize Protein in a Patient With Corn-Dependent Exercise-Induced Anaphylaxis: A Case Report. [PDF]
Goto A +4 more
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Deep Learning-Guided Identification and In Vivo Validation of Compact Cis-Regulatory Elements for the Zebrafish Habenula. [PDF]
Li Z, Liu S, Zhang Q, Zhang C, Peng G.
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Predicting non-specific binding of VHHs using machine learning models with cluster-aware validation. [PDF]
Stanev V +18 more
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Experimentally induced mood changes and simultaneously changing heart rate variability (HRV). [PDF]
Vroemen M +3 more
europepmc +1 more source
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Molecular Survey and Genetic Characterization of <i>Tetratrichomonas buttreyi</i> and <i>Pentatrichomonas hominis</i> in Horses in Shanxi Province, Northern China. [PDF]
Wang DY +5 more
europepmc +1 more source

