Results 91 to 100 of about 6,258,452 (248)

Spotlight on post-transcriptional control in the circadian system

, 2010
Staiger D, Köster T. Spotlight on post-transcriptional control in the circadian system. Cellular and Molecular Life Sciences. 2011;68(1):71-83.An endogenous timing mechanism, the circadian clock, causes rhythmic expression of a considerable fraction of ...
Tino Köster, Köster, Tino ; https://orcid.org/, Staiger, Dorothee, Dorothee Staiger   +3 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Post-transcriptional modification of m⁶A methylase METTL3 regulates ERK-induced androgen-deprived treatment resistance prostate cancer. [PDF]

Cell Death Dis, 2023
Li Y, Zhu S, Chen Y, Ma Q, Kan D, Yu W, Zhang B, Chen X, Wei W, Shao Y, Wang K, Zhang M, Deng S, Niu Y, Shang Z.   +14 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Fine-tuning thermogenesis from the post-transcriptional level

iScience
Summary: In mammals, adipose tissue is involved in energy homeostasis regulation. White adipose tissue (WAT) is the major energy storage site for mammals, whereas brown adipose tissue (BAT) is involved in energy expenditure and thermogenesis.
Mengyao Wan, Hao Gu, Siyuan Chen, Zihao Guo, Bayindala Xiagedeer, Yaqun Guan, Xiaodi Liang   +6 more
doaj   +1 more source

Transcriptome-wide m⁶A profiling reveals mRNA post-transcriptional modification of boar sperm during cryopreservation. [PDF]

BMC Genomics, 2021
Qin Z, Wang W, Ali MA, Wang Y, Zhang Y, Zhang M, Zhou G, Yang JD, Zeng C.   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The RNA world in plants: Post-transcriptional control III

, 2001
*This article is free to read on the publisher's website*\ud \ud Post-transcriptional control of gene expression has gone from a curiosity involving a few special genes to a highly diverse and widespread set of processes that is truly pervasive in plant ...
John W. S. Brown, Karen S. Browning, Miller, W. A., Peter M. Waterhouse, Brown, J. W. S., Browning, K. S., W. Allen Miller, Waterhouse, P. M.   +7 more
core   +1 more source

Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivo

Nature Communications, 2019
The post-transcriptional modification of mRNAs provides an additional layer to gene expression regulation. Here the authors show that 2′-O-methylation mediated by box C/D snoRNAs and fibrillarin can inhibit the translation of target mRNAs.
Brittany A. Elliott, Hsiang-Ting Ho, Srivathsan V. Ranganathan, Sweta Vangaveti, Olga Ilkayeva, Hala Abou Assi, Alex K. Choi, Paul F. Agris, Christopher L. Holley   +8 more
doaj   +1 more source

Dysregulation of post-transcriptional modification by copy number variable microRNAs in schizophrenia with enhanced glycation stress. [PDF]

Transl Psychiatry, 2021
Yoshikawa A, Kushima I, Miyashita M, Toriumi K, Suzuki K, Horiuchi Y, Kawaji H, Takizawa S, Ozaki N, Itokawa M, Arai M.   +10 more
europepmc   +1 more source