Results 61 to 70 of about 1,013,149 (279)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
RNA editing in cardiovascular health and disease
Post-transcriptional RNA modifications can alter RNA structure, stability, localization, and function. Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional modification that converts adenosine nucleotides in RNA to inosine nucleotides ...
Xiaoxin Huang +3 more
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Catalogue of post-editing tools [PDF]
La postedició com a alternativa per augmentar la productivitat està esdevenint una activitat cada cop més habitual en la nostra indústria. En aquest catàleg es presenten algunes de les eines disponibles en l’actualitat que ofereixen la funcionalitat ...
Flórez, Silvia
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Can Automatic Post-Editing Make MT More Meaningful? [PDF]
Automatic post-editors (APEs) enable the re-use of black box machine translation (MT) systems for a variety of tasks where different aspects of translation are important. In this paper, we describe APEs that target adequacy errors, a critical problem for
de Gispert, Adria +4 more
core +2 more sources
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
USING MACHINE TRANSLATION ENGINES IN THE CLASSROOM: A SURVEY OF TRANSLATION STUDENTS’ PERFORMANCE
This paper outlines the results of the experimental study aiming to explore the impact of using machine translation engines on the performance of translation students. Machine translation engines refer to the software developed to translate source texts
Alla Olkhovska, Iryna Frolova
doaj +1 more source
Automatic Post-Editing for Vietnamese
Accepted to ALTA ...
Vu, Thanh, Nguyen, Dai Quoc
openaire +2 more sources

