Results 1 to 10 of about 197,880 (142)

Necroptosis in cancer: insight from epigenetic, post-transcriptional and post-translational modifications [PDF]

Journal of Hematology & Oncology
Necroptosis represents a distinct form of programmed cell death that exhibits characteristics of both necrosis and apoptosis. Due to its potential to activate anti-cancer immune responses, utilizing necroptosis to enhance immune activity within the tumor
Jinxin Tang, Yan Zhuang, Yibo Zhang, Hongkun Hu, Hua Wang, Haodong Xu, Yintao Li, Chao Tu   +7 more
doaj   +3 more sources

MiRNA post-transcriptional modification dynamics in T cell activation [PDF]

iScience, 2021
Summary: T cell activation leads to extensive changes in the miRNA repertoire. Although overall miRNA expression decreases within a few hours of T cell activation, some individual miRNAs are specifically upregulated.
Ana Rodríguez-Galán, Sara G. Dosil, Manuel José Gómez, Irene Fernández-Delgado, Lola Fernández-Messina, Fátima Sánchez-Cabo, Francisco Sánchez-Madrid   +6 more
doaj   +2 more sources

Post-Transcriptional Regulation of Viral RNA through Epitranscriptional Modification [PDF]

Cells, 2021
The field of mRNA modifications has been steadily growing in recent years as technologies have improved and the importance of these residues became clear.
David G. Courtney
doaj   +2 more sources

m1A Post‐Transcriptional Modification in tRNAs [PDF]

Biomolecules, 2017
To date, about 90 post‐transcriptional modifications have been reported in tRNA expanding their chemical and functional diversity. Methylation is the most frequent post‐transcriptional tRNA modification that can occur on almost all nitrogen sites of
Stephanie Oerum, Clément Dégut, Pierre Barraud, Carine Tisné   +3 more
doaj   +2 more sources

An extended dsRBD is required for post-transcriptional modification in human tRNAs. [PDF]

Nucleic Acids Res, 2015
Bou-Nader C, Pecqueur L, Bregeon D, Kamah A, Guérineau V, Golinelli-Pimpaneau B, Guimarães BG, Fontecave M, Hamdane D.   +8 more
europepmc   +3 more sources

m6A-modified LINC02418 induces transcriptional and post-transcriptional modification of CTNNB1 via interacting with YBX1 and IGF2BP1 in colorectal cancer. [PDF]

Cell Death Discov
Zhang H, Han Y, Wu C, Wang S, Chen M, Xu Q, Wei H, Zhou X, Wang G.   +8 more
europepmc   +2 more sources

Editorial: Post-transcriptional modifications in cancer immunity and immunotherapy. [PDF]

Front Immunol
Wei G, Zhou Y, Yue T, Zhang D.
europepmc   +2 more sources

Regulatory role of RNA N6-methyladenosine modifications during skeletal muscle development

Frontiers in Cell and Developmental Biology, 2022
Functional cells in embryonic myogenesis and postnatal muscle development undergo multiple stages of proliferation and differentiation, which are strict procedural regulation processes.
Baojun Yu, Jiamin Liu, Juan Zhang, Tong Mu, Xiaofang Feng, Ruoshuang Ma, Yaling Gu   +6 more
doaj   +1 more source

The Potential Role of m⁶A in the Regulation of TBI-Induced BGA Dysfunction

Antioxidants, 2022
The brain–gut axis (BGA) is an important bidirectional communication pathway for the development, progress and interaction of many diseases between the brain and gut, but the mechanisms remain unclear, especially the post-transcriptional regulation of ...
Peizan Huang, Min Liu, Jing Zhang, Xiang Zhong, Chunlong Zhong   +4 more
doaj   +1 more source

Interplay of four types of RNA modification writers revealed distinct tumor microenvironment and biological characteristics in pancreatic cancer

Frontiers in Immunology, 2022
BackgroundPancreatic cancer (PC) is one of the most lethal malignancies and carries a dismal mortality and morbidity. Four types of RNA modification (namely m6A, m1A, APA and A-to-I) could be catalyzed by distinct enzymatic compounds (“writers ...
Wenzhe Gao, Dongjie Chen, Dongjie Chen, Dongjie Chen, Dongjie Chen, Jixing Liu, Jixing Liu, Longjun Zang, Tijun Xiao, Xianlin Zhang, Zheng Li, Hongwei Zhu, Xiao Yu   +12 more
doaj   +1 more source