Mapping post-transcriptional modifications in Staphylococcus aureus tRNAs by nanoLC/MSMS
Biochimie, 2019 RNA modifications are involved in numerous biological processes. These modifications are constitutive or modulated in response to adaptive processes and can impact RNA base-pairing formation, protein recognition, RNA structure and stability. tRNAs are the most abundantly modified RNA molecules.
Laura Antoine +4 more
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Influence of Sox protein SUMOylation on neural development and regeneration
Neural Regeneration Research, 2022 SRY-related HMG-box (Sox) transcription factors are known to regulate central nervous system development and are involved in several neurological diseases.
Kun-Che Chang
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Post‐transcriptional modification of tyrosine tRNA as a function of growth in Bacillus subtilis [PDF]
FEBS Letters, 1976 G. Keith +4 more
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Control of Biosynthesis and Post-Transcriptional Modification of the Progesterone Receptor [PDF]
Biology of Reproduction, 1992 The rabbit progesterone receptor undergoes dual regulation at the level of transcription: positive by estrogens and negative by progestins. The two aspects of this regulation are mediated by a single intragenic estrogen-responsive element. Estrogen receptor binding to this element has been demonstrated but progestin down-regulation does not proceed ...
Anne Chauchereau +2 more
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Epigenetics, 2021 To investigate the detailed functions and underlying mechanisms of miR-518a-5p/CCR6 in diffuse large B cell lymphoma (DLBCL) is needed. In this study, CCR6 expression levels were tested both in DLBCL cell lines and specimens.
Qian Huang +3 more
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Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]
, 2015 Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C +2 more
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Expanding the Nucleotide Repertoire of the Ribosome with Post-Transcriptional Modifications [PDF]
ACS Chemical Biology, 2007 In all kingdoms of life, RNAs undergo specific post-transcriptional modifications. More than 100 different analogues of the four standard RNA nucleosides have been identified. Modifications in ribosomal RNAs (rRNAs) are highly prevalent and cluster in regions of the ribosome that have functional importance, have a high level of nucleotide conservation,
Tek N. Lamichhane +2 more
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Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcription factors [PDF]
, 1993 Extinction is defined as the loss of cell type-specific gene expression that occurs in somatic cell hybrids derived by fusion of cells with dissimilar phenotypes.
Boshart, Michael +2 more
core +1 more source
Biosynthesis and functions of sulfur modifications in tRNA
Frontiers in Genetics, 2014 Sulfur is an essential element for a variety of cellular constituents in all living organisms. In tRNA molecules, there are many sulfur-containing nucleosides, such as the derivatives of 2‑thiouridine (s2U), 4-thiouridine (s4U), 2-thiocytidine (s2C), and
Naoki eShigi
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Regulation of PD-L1 expression in the tumor microenvironment
Journal of Hematology & Oncology, 2021 Programmed death-ligand 1 (PD-L1) on cancer cells engages with programmed cell death-1 (PD-1) on immune cells, contributing to cancer immune escape. For multiple cancer types, the PD-1/PD-L1 axis is the major speed-limiting step of the anti-cancer immune
Ming Yi +4 more
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