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The cladoceran crustacean Daphnia produces only females by parthenogenesis in a healthy population. However, in response to environmental declines such as crowding and lack of foods, it produces eggs destined to become males that are genetically ...
Yasuhiko Kato, Hajime Watanabe
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FOXM1 and Cancer: Faulty Cellular Signaling Derails Homeostasis
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue homeostasis, angiogenesis, apoptosis, and redox signaling.
Dhanya Kalathil+4 more
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Regulatory role of RNA N6-methyladenosine modifications during skeletal muscle development
Functional cells in embryonic myogenesis and postnatal muscle development undergo multiple stages of proliferation and differentiation, which are strict procedural regulation processes.
Baojun Yu+6 more
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Regulation of the master regulator FOXM1 in cancer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the processes of cell proliferation, self-renewal, and tumorigenesis.
Guo-Bin Liao+7 more
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A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon
The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea.
Alan P. R. Lorenzetti+11 more
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Post-transcriptional regulation of ribosome biogenesis in yeast
Most microorganisms are exposed to the constantly and often rapidly changing environment. As such they evolved mechanisms to balance their metabolism and energy expenditure with the resources available to them.
Isabelle C. Kos-Braun, Martin Koš
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Seed germination is the process through which a quiescent organ reactivates its metabolism culminating with the resumption cell divisions. It is usually the growth of a plant contained within a seed and results in the formation of a seedling.
Xiaofei Xue+10 more
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DDX6 (p54/RCK) is a human RNA helicase with central roles in mRNA decay and translation repression. To help our understanding of how DDX6 performs these multiple functions, we conducted the first unbiased, large-scale study to map the DDX6-centric ...
Rebecca Bish+6 more
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Are microRNAs Important Players in HIV-1 Infection? An Update
HIV-1 has already claimed over 35 million human lives globally. No curative treatments are currently available, and the only treatment option for over 36 million people currently living with HIV/AIDS are antiretroviral drugs that disrupt the function of ...
Muthukumar Balasubramaniam+2 more
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Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms
MicroRNAs (miRNAs) function as the post-transcriptional factor that finetunes the gene expression by targeting to the specific candidate. Mis-regulated expression of miRNAs consequently disturbs gene expression profile, which serves as the pivotal ...
Ying-Chin Lin+4 more
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