Results 11 to 20 of about 694,082 (344)
Post-transcriptional regulation across human tissues. [PDF]
PLoS Computational Biology, 2017 Transcriptional and post-transcriptional regulation shape tissue-type-specific proteomes, but their relative contributions remain contested. Estimates of the factors determining protein levels in human tissues do not distinguish between (i) the factors ...
Alexander Franks +2 more
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Post-transcriptional regulation: The dawn of PTB [PDF]
Current Biology, 1997 The ‘polypyrimidine-tract-binding protein’ (PTB) participates in the control of alternative processing and translation of various RNAs, and may operate as a multifunctional regulator of tissue-specific gene ...
Gebauer, Fátima, Valcárcel, Juan
core +4 more sources
Post-transcriptional regulation of ribosome biogenesis in yeast
Microbial Cell, 2017 Most microorganisms are exposed to the constantly and often rapidly changing environment. As such they evolved mechanisms to balance their metabolism and energy expenditure with the resources available to them.
Isabelle C. Kos-Braun, Martin Koš
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Quick change: post-transcriptional regulation in Pseudomonas [PDF]
FEMS Microbiology Letters, 2017 Pseudomonas species have evolved dynamic and intricate regulatory networks to fine-tune gene expression, with complex regulation occurring at every stage in the processing of genetic information.
Afonyushkin +76 more
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Role of Sam68 in post-transcriptional gene regulation [PDF]
International Journal of Molecular Sciences, 2013 The STAR family of proteins links signaling pathways to various aspects of post-transcriptional regulation and processing of RNAs. Sam68 belongs to this class of heteronuclear ribonucleoprotein particle K (hnRNP K) homology (KH) single domain-containing ...
Anderson +130 more
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Post-transcriptional Regulation of NK Cell Activation [PDF]
Immune Network, 2009 Natural killer (NK) cells play key roles in innate and adaptive immune defenses. NK cell responses are mediated by two major mechanisms: the direct cytolysis of target cells, and immune regulation by production of various cytokines. Many previous reports
Aggarwal +46 more
core +6 more sources
Regulation of Proteasome Activity by (Post-)transcriptional Mechanisms [PDF]
Frontiers in Molecular Biosciences, 2019 Intracellular protein synthesis, folding, and degradation are tightly controlled processes to ensure proper protein homeostasis. The proteasome is responsible for the degradation of the majority of intracellular proteins, which are often targeted for ...
Suzan Kors +3 more
doaj +4 more sources
Post-transcriptional regulation during stress. [PDF]
FEMS Yeast Res, 2022 AbstractTo remain competitive, cells exposed to stress of varying duration, rapidity of onset, and intensity, have to balance their expenditure on growth and proliferation versus stress protection. To a large degree dependent on the time scale of stress exposure, the different levels of gene expression control: transcriptional, post-transcriptional ...
Hernández-Elvira M, Sunnerhagen P.
europepmc +3 more sources
Dynamics of transcriptional and post-transcriptional regulation [PDF]
Briefings in Bioinformatics, 2020 AbstractDespite gene expression programs being notoriously complex, RNA abundance is usually assumed as a proxy for transcriptional activity. Recently developed approaches, able to disentangle transcriptional and post-transcriptional regulatory processes, have revealed a more complex scenario.
Furlan M, De Pretis S, Pelizzola M
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Post‐transcriptional regulation in cancer [PDF]
Biology of the Cell, 2004 Summry— Deregulation of gene expression is a hallmark of the cancer cell. Acquiring a new profile of expressed proteins may enable the cell to re‐enter the cell cycle, or give them a growth or motility advantage over “normal cells”. An efficient and rapid way to alter gene expression is via regulation of mRNAs already transcribed. Modifications of mRNA
Audic, Yann, Hartley, Rebecca
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