Results 11 to 20 of about 771,641 (331)
Post-transcriptional regulation across human tissues.
PLoS Computational Biology, 2017 Transcriptional and post-transcriptional regulation shape tissue-type-specific proteomes, but their relative contributions remain contested. Estimates of the factors determining protein levels in human tissues do not distinguish between (i) the factors ...
Alexander Franks +2 more
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Quick change: post-transcriptional regulation in Pseudomonas [PDF]
FEMS Microbiology Letters, 2017 Pseudomonas species have evolved dynamic and intricate regulatory networks to fine-tune gene expression, with complex regulation occurring at every stage in the processing of genetic information.
Afonyushkin +76 more
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Post‐transcriptional regulation in cancer [PDF]
Biology of the Cell, 2004 Summry— Deregulation of gene expression is a hallmark of the cancer cell. Acquiring a new profile of expressed proteins may enable the cell to re‐enter the cell cycle, or give them a growth or motility advantage over “normal cells”. An efficient and rapid way to alter gene expression is via regulation of mRNAs already transcribed. Modifications of mRNA
Audic, Yann, Hartley, Rebecca
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Post-transcriptional regulation during stress
FEMS Yeast Research, 2022 AbstractTo remain competitive, cells exposed to stress of varying duration, rapidity of onset, and intensity, have to balance their expenditure on growth and proliferation versus stress protection. To a large degree dependent on the time scale of stress exposure, the different levels of gene expression control: transcriptional, post-transcriptional ...
Mariana Hernández-Elvira +1 more
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Prokineticin-Receptor Network: Mechanisms of Regulation
Life, 2022 Prokineticins are a new class of chemokine-like peptides that bind their G protein-coupled receptors, PKR1 and PKR2, and promote chemotaxis and the production of pro-inflammatory cytokines following tissue injury or infection.
Roberta Lattanzi, Rossella Miele
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A Quarter Century History of ATML1 Gene Research
Plants, 2021 The cloning of the ATML1 gene, encoding an HD-ZIP class IV transcription factor, was first reported in 1996. Because ATML1 mRNA was preferentially detected in the shoot epidermis, cis-regulatory sequences of ATML1 have been used to drive gene expression ...
Hiroyuki Iida, Shinobu Takada
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Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases
Viruses, 2021 Lentiviral vectors are the most frequently used tool to stably transfer and express genes in the context of gene therapy for monogenic diseases. The vast majority of clinical applications involves an ex vivo modality whereby lentiviral vectors are used ...
Valentina Poletti, Fulvio Mavilio
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Frontiers in Cell and Developmental Biology, 2022 The cladoceran crustacean Daphnia produces only females by parthenogenesis in a healthy population. However, in response to environmental declines such as crowding and lack of foods, it produces eggs destined to become males that are genetically ...
Yasuhiko Kato, Hajime Watanabe
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FOXM1 and Cancer: Faulty Cellular Signaling Derails Homeostasis
Frontiers in Oncology, 2021 Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue homeostasis, angiogenesis, apoptosis, and redox signaling.
Dhanya Kalathil +4 more
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Regulatory role of RNA N6-methyladenosine modifications during skeletal muscle development
Frontiers in Cell and Developmental Biology, 2022 Functional cells in embryonic myogenesis and postnatal muscle development undergo multiple stages of proliferation and differentiation, which are strict procedural regulation processes.
Baojun Yu +6 more
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