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A Quarter Century History of ATML1 Gene Research
The cloning of the ATML1 gene, encoding an HD-ZIP class IV transcription factor, was first reported in 1996. Because ATML1 mRNA was preferentially detected in the shoot epidermis, cis-regulatory sequences of ATML1 have been used to drive gene expression ...
Hiroyuki Iida, Shinobu Takada
doaj +1 more source
Post-Transcriptional Control in the Regulation of Polyhydroxyalkanoates Synthesis [PDF]
The large production of non-degradable petrol-based plastics has become a major global issue due to its environmental pollution. Biopolymers produced by microorganisms such as polyhydroxyalkanoates (PHAs) are gaining potential as a sustainable alternative, but the high cost associated to their industrial production has been a limiting factor.
Alexandra Peregrina+4 more
openaire +4 more sources
Probing the limits to microRNA-mediated control of gene expression [PDF]
According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying significant potential implications for a variety of biological processes.
De Martino, Andrea+3 more
core +11 more sources
The cladoceran crustacean Daphnia produces only females by parthenogenesis in a healthy population. However, in response to environmental declines such as crowding and lack of foods, it produces eggs destined to become males that are genetically ...
Yasuhiko Kato, Hajime Watanabe
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FOXM1 and Cancer: Faulty Cellular Signaling Derails Homeostasis
Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue homeostasis, angiogenesis, apoptosis, and redox signaling.
Dhanya Kalathil+4 more
doaj +1 more source
Noise processing by microRNA-mediated circuits: The Incoherent Feed-Forward Loop, revisited [PDF]
The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably protein levels. The discovery of small non-coding RNAs (miRNAs) in specific
De Martino, Andrea+3 more
core +7 more sources
Regulatory role of RNA N6-methyladenosine modifications during skeletal muscle development
Functional cells in embryonic myogenesis and postnatal muscle development undergo multiple stages of proliferation and differentiation, which are strict procedural regulation processes.
Baojun Yu+6 more
doaj +1 more source
Post-transcriptional regulation of the pluripotent state [PDF]
Pluripotency describes the developmental capacity to give rise to all cell types in the adult body. A comprehensive understanding of the molecular mechanisms that regulate pluripotency is important for both basic and translational research. While earlier studies mostly focused on signaling pathways, transcriptional regulation, and epigenetic ...
Guang Hu, Qing Chen
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Regulation of the master regulator FOXM1 in cancer
FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the processes of cell proliferation, self-renewal, and tumorigenesis.
Guo-Bin Liao+7 more
doaj +1 more source
Circadian rhythms and post-transcriptional regulation in higher plants [PDF]
The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Romanowski, Andrés+1 more
core +3 more sources