Results 141 to 150 of about 6,398,571 (341)
BMC Microbiology, 2012 Background PII proteins have a fundamental role in the control of nitrogen metabolism in bacteria, through interactions with different PII targets, controlled by metabolite binding and post-translational modification, uridylylation in most organisms.
Teixeira Pedro +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
The Human Thioredoxin System: Modifications and Clinical Applications [PDF]
Iranian Journal of Basic Medical Sciences, 2011 The thioredoxin system, comprising thioredoxin (Trx), thioredoxin reductase (TrxR) and NADPH, is one of the major cellular antioxidant systems, implicated in a large and growing number of biological functions.
Seyed Isaac Hashemy
doaj
Diverse regulatory manners of human telomerase reverse transcriptase
Cell Communication and Signaling, 2019 Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase and plays important roles in human cancers. Aberrant expression of hTERT is closely associated with tumorigenesis, cancer cell stemness maintaining, cell proliferation,
Meng-Meng Jie +9 more
doaj +1 more source
DAPPLE 2: a Tool for the Homology-Based Prediction of Post-Translational Modification Sites
, 2016 The post-translational modification of proteins is critical for regulating their function. Although many post-translational modification sites have been experimentally determined, particularly in certain model organisms, experimental knowledge of these ...
Farhad Maleki (2878241) +3 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
dbPTM 2016: 10-year anniversary of a resource for post-translational modification of proteins
Nucleic Acids Res., 2015 Owing to the importance of the post-translational modifications (PTMs) of proteins in regulating biological processes, the dbPTM (http://dbPTM.mbc.nctu.edu.tw/) was developed as a comprehensive database of experimentally verified PTMs from several ...
Kai-Yao Huang +7 more
semanticscholar +1 more source
Post-translational modification of proteins [PDF]
, 2018 Posttranslacijska modifikacija svaka je preinaka proteina koja se odvija na proteinu nakon njegove biosinteze. Ove modifikacije uključuju smatanje proteina te mnogobrojne kovalentne modifikacije.
Valla, Robert
core
Subcellular differences in post-translational modification of barley 14-3-3 proteins
, 2000 Expression and post-translational modification of barley 14-3-3 isoforms, 14-3-3A, 14-3-3B and 14-3-3C, were investigated using isoform-specific antibodies.
Jan W. Kijne +7 more
core +1 more source