Results 51 to 60 of about 6,398,571 (341)
Cell Communication and Signaling, 2023 Background Lysine carbamylation is a biomarker of rheumatoid arthritis and kidney diseases. However, its cellular function is understudied due to the lack of tools for systematic analysis of this post-translational modification (PTM).
Youngki You +9 more
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Conservation profile of nsSNPs in FOXP2 protein and their post translational modification.
, 2022 Conservation profile of nsSNPs in FOXP2 protein and their post translational modification.
Fahmida Sultana Rima (13222422) +3 more
core +1 more source
Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology
Frontiers in Immunology, 2020 Most extracellular proteins are secreted via the classical endoplasmic reticulum (ER)/Golgi-dependent secretion pathway; however, some proteins, including a few danger-associated molecular patterns (DAMPs), are secreted via non-classical ER/Golgi ...
M. Kwak +5 more
semanticscholar +1 more source
Biosynthesis and functions of sulfur modifications in tRNA
Frontiers in Genetics, 2014 Sulfur is an essential element for a variety of cellular constituents in all living organisms. In tRNA molecules, there are many sulfur-containing nucleosides, such as the derivatives of 2‑thiouridine (s2U), 4-thiouridine (s4U), 2-thiocytidine (s2C), and
Naoki eShigi
doaj +1 more source
Post-translational Modification Regulates Formation and Cargo-Loading of Extracellular Vesicles
Frontiers in Immunology, 2020 Accumulating evidence suggests that post-translational modifications (PTMs) regulate the selective encapsulation of non-coding RNA molecules into extracellular vesicles (EVs) and contribute to the downstream functions of EVs or EV-cargo non-coding RNAs ...
Jonathan M. Carnino, K. Ni, Yang Jin
semanticscholar +1 more source
Post-translational modifications of transporters
Pharmacology & Therapeutics, 2018 Drug transporter proteins are critical to the distribution of a wide range of endogenous compounds and xenobiotics such as hormones, bile acids, peptides, lipids, sugars, and drugs. There are two classes of drug transporters- the solute carrier (SLC) transporters and ATP-binding cassette (ABC) transporters -which predominantly differ in the energy ...
Lindsay C, Czuba +2 more
openaire +3 more sources
Post-Translational Modification of Lamins: Mechanisms and Functions
Frontiers in Cell and Developmental Biology, 2022 Lamins are the ancient type V intermediate filament proteins contributing to diverse biological functions, such as the maintenance of nuclear morphology, stabilization of chromatin architecture, regulation of cell cycle progression, regulation of spatial-
Mingyue Zheng +2 more
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Scientific Reports, 2022 AMPylation is an emerging post-translational modification that occurs on the hydroxyl group of threonine, serine, or tyrosine via a phosphodiester bond. AMPylators catalyze this process as covalent attachment of adenosine monophosphate to the amino acid ...
Sayed Mehedi Azim +4 more
doaj +1 more source
Post-translational protein modifications in schizophrenia [PDF]
npj Schizophrenia, 2020 AbstractResearch investigating the pathophysiology of schizophrenia has not yet precisely defined the molecular phenotype of this disorder. Many studies have investigated cellular dysfunction by examining expression levels of molecular targets in postmortem patient brain; however, inconsistencies between transcript and protein measures in schizophrenia
Toni M. Mueller +1 more
openaire +2 more sources
iProteinDB: An Integrative Database of Drosophila Post-translational Modifications
G3: Genes, Genomes, Genetics, 2019 Post-translational modification (PTM) serves as a regulatory mechanism for protein function, influencing their stability, interactions, activity and localization, and is critical in many signaling pathways.
Yanhui Hu +10 more
doaj +1 more source