Results 221 to 230 of about 85,477 (330)

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Antagonistic histone post-translational modifications improve the fidelity of epigenetic inheritance - a Bayesian perspective. [PDF]

Epigenetics Chromatin
Prabhu BNB, Soni AN, Pillai SRB, Ramakrishnan N.   +3 more
europepmc   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Post-translational modifications in ovarian cancer: implications for immunotherapy: a mini-review. [PDF]

J Ovarian Res
Sun L, Guo YF, Duan CC, Chen C, Xiao L.
europepmc   +1 more source

Missense3D-PTMdb an interactive web resource to explore and visualize genetic variants and post-translational modifications sites (PTMs) using AlphaFold 3D models

Haotian Zhao, Ryan Pye, Gemma Walker, Wendy Tran, Olivia Simmonds, Ifigenia Tsitsa, Suhail A. Islam, Gordon Hanna, Alessia David   +8 more
openalex   +1 more source

Roles of N‐terminal acetyltransferase complex in phytopathogenic fungi: Promoting diseases with different mechanisms

New Plant Protection, EarlyView.
The N‐terminal acetyltransferase A (NatA) complex‐mediated protein acetylation plays key regulatory roles in pathogenesis through different mechanisms, highlighting the potential of targeting NatA complexes as effective strategies for plant disease management.
Mengmeng Guo, Yizhou Gao, Leeza Tariq, Fengming Song   +3 more
wiley   +1 more source

Mechanistic insights into post-translational modifications in hepatic fibrosis: pathogenic roles and therapeutic potentials. [PDF]

J Transl Med
Bai X, Liu Z, Li X, Sun R, Yu Z.
europepmc   +1 more source

MTPrompt-PTM: A Multi-Task Method for Post-Translational Modification Prediction Using Prompt Tuning on a Structure-Aware Protein Language Model

Ye Jin Han, Fei He, Qing Shao, Duolin Wang, Dong Xu   +4 more
openalex   +1 more source

Sample Preparation for Multi‐Omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow

PROTEOMICS, EarlyView.
ABSTRACT Advances in methodologies and technologies over the past decade have led to an unprecedented depth of analysis of a cell's biomolecules, with entire genomes able to be sequenced in hours and up to 10,000 transcripts or ORF products (proteins) able to be quantified from a single cell.
Breyer Woodland, Luke A. Farrell, Lana Brockbals, Maria Rezcallah, Aiden Brennan, Emily J. Sunnucks, Sam T. Gould, Aleksandra M. Stanczak, Matthew B. O'Rourke, Matthew P. Padula   +9 more
wiley   +1 more source

Single-cell and spatial transcriptomics reveal post-translational modifications in osteosarcoma progression and tumor microenvironment. [PDF]

PLoS One
Cui Y, Wu Y, Jiang D, Ding T.
europepmc   +1 more source