Results 111 to 120 of about 10,304,482 (352)

Brain‐specific potential guanine nucleotide exchange factor for Arf, synArfGEF (Po), is localized to postsynaptic density

open access: yesJournal of Neurochemistry, 2004
We cloned from a rat brain cDNA library a novel cDNA and named it a potential synaptic guanine nucleotide exchange factor (GEF) for Arf (synArfGEF (Po)) (GenBank Accession no. AB057643) based on its domain structure and localization.
Y. Inaba   +10 more
semanticscholar   +1 more source

Learning of Precise Spike Times with Membrane Potential Dependent Synaptic Plasticity [PDF]

open access: yesarXiv, 2014
Precise spatio-temporal patterns of neuronal action potentials underly e.g. sensory representations and control of muscle activities. However, it is not known how the synaptic efficacies in the neuronal networks of the brain adapt such that they can reliably generate spikes at specific points in time.
arxiv  

Rectified Linear Postsynaptic Potential Function for Backpropagation in Deep Spiking Neural Networks [PDF]

open access: yesarXiv, 2020
Spiking Neural Networks (SNNs) use spatio-temporal spike patterns to represent and transmit information, which is not only biologically realistic but also suitable for ultra-low-power event-driven neuromorphic implementation. Motivated by the success of deep learning, the study of Deep Spiking Neural Networks (DeepSNNs) provides promising directions ...
arxiv  

Gate‐Tunable Dual‐Mode Optoelectronic Device for Self‐Powered Photodetector and Optoelectronic Synapse

open access: yesAdvanced Science, EarlyView.
A gate‐tunable MoTe₂/MoS₂ heterostructure‐based dual‐mode optoelectronic device functions as both a self‐powered photodetector and an optoelectronic synapse. It leverages the photovoltaic effect for photodetection and trapping states for synaptic behavior. Gate modulation enables seamless switching, paving the way for integrating neuromorphic computing
Yi Ouyang   +5 more
wiley   +1 more source

Postsynaptic activity of inhibitory neurons evokes hemodynamic fMRI responses

open access: yesNeuroImage, 2021
Functional MRI responses are localized to the synaptic sites of evoked inhibitory neurons, but it is unknown whether, or by what mechanisms, these neurons initiate functional hyperemia.
Alexander John Poplawsky   +4 more
doaj  

Differential expression of an inwardly rectifying chloride conductance in rat brain neurons: a potential mechanism for cell-specific modulation of postsynaptic inhibition

open access: yesJournal of Neuroscience, 1995
A voltage-sensitive inwardly rectifying chloride (Cl-) conductance (GCl(V) is present in hippocampal pyramidal but not dentate gyrus neurons and has a significant role in modulation of neuronal inhibition by GABA.
RL Smith   +4 more
semanticscholar   +1 more source

Regulation of PVT‐CeA Circuit in Deoxynivalenol‐Induced Anorexia and Aversive‐Like Emotions

open access: yesAdvanced Science, EarlyView.
The study investigates Deoxynivalenol (DON) effects on feeding and emotions, focusing on the central amygdala (CeA). Acute DON exposure reduces food intake and alters behavior, linked to CeAGABA neuron activity and PVT‐CeA connectivity. Manipulating CeAGABA neurons and using SCN10A antagonist A‐803467 alleviate DON's effects, offering potential ...
Liu‐Nan Yang   +4 more
wiley   +1 more source

Bioinspired Adaptive Neuron Enabled by Self‐powered Optoelectronic Memristor and Threshold Switching Memory for Neuromorphic Visual System

open access: yesAdvanced Science, EarlyView.
The self‐powered optoelectronic memristor based on ZnO/WOx heterojunction is developed, exhibiting the visual adaptation functions of desensitization and Weber's law. A bioinspired visual adaptive neuron is constructed, capable of converting light stimuli into dynamic spike trains.
Yankun Cheng   +8 more
wiley   +1 more source

Loss of tumor necrosis factor (TNF)‐receptor 1 and TNF‐receptor 2 partially replicate effects of TNF deficiency on dendritic spines of granule cells in mouse dentate gyrus

open access: yesJournal of Comparative Neurology, Volume 531, Issue 2, Page 281-293, February 2023., 2023
Hippocampal granule cells of adult mice lacking canonical TNF‐Rs were filled with Alexa568 and immunolabeled for Synaptopodin. Morphometric analysis of their spines revealed that TNF‐R mutants partially replicate changes previously reported for TNF‐deficient mice.
Dinko Smilovic   +5 more
wiley   +1 more source

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats

open access: yesIranian Journal of Medical Sciences, 2016
Background: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown.
Chengdong Yuan   +6 more
doaj  

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