Results 191 to 200 of about 433,552 (252)

Molecular organization of central cholinergic synapses. [PDF]

Proc Natl Acad Sci U S A
Rosenthal JS, Zhang D, Yin J, Long C, Yang G, Li Y, Lu Z, Li WP, Yu Z, Li J, Yuan Q.   +10 more
europepmc   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Dexmedetomidine Reduces Presynaptic γ-Aminobutyric Acid Release and Prolongs Postsynaptic Responses in Layer 5 Pyramidal Neurons in the Primary Somatosensory Cortex of <i>Mice</i>. [PDF]

Int J Mol Sci
Tang B, Tang J, Huang Y.
europepmc   +1 more source

Alcohol‐sensitive MoS2 optoelectronic synapses for mimicking human‐like visual adaptation

InfoMat, EarlyView.
This work demonstrates MoS2 optoelectronic synapses with tunable human‐like visual adaptation to alcohol concentrations, featuring remarkable photo‐induced conductance plasticity for emulating alcohol‐sensitive human visual recognition. By controlling doping levels and applying optoelectronic stimuli, the device can emulate human‐like behaviors such as
Xiao Liu, Ming Huang, Xiongfeng Zou, Wajid Ali, Sajid Ur Rehman, Juan Li, Ziwei Li, Li Xiang, Anlian Pan   +8 more
wiley   +1 more source

Dorsal-Caudal and Ventral Hippocampi Target Different Cell Populations in the Medial Frontal Cortex in Rodents. [PDF]

J Neurosci
Alemán-Andrade P, Witter MP, Tsutsui KI, Ohara S.   +3 more
europepmc   +1 more source

In‐sensor reservoir computing for biometric identification based on MoTe2/BaTiO3 optical synapses

InfoMat, EarlyView.
An in‐sensor RC system with MoTe2/BTO optical synaptic array for face and fingerprint recognition. (A) The optical synapses first detect important face and fingerprint optical information in the human, and then transmit them to the optical reservoir, which is responsible for projecting the input information into feature space.
Zhenqiang Guo, Gongjie Liu, Weifeng Zhang, Xinhao Li, Zhen Zhao, Qiuhong Li, Haoqi Liu, Xiaobing Yan   +7 more
wiley   +1 more source

Targeting the Neuro-vascular Presynaptic Signalling in STROKE: Evidence and Therapeutic Implications. [PDF]

Ann Neurosci
Maikap S, Lucaciu A, Chakraborty A, Kestner RI, Vutukuri R, Annamneedi A.   +5 more
europepmc   +1 more source

Dexmedetomidine as a Ropivacaine Adjuvant in a Thoracic Paravertebral Block Combined With an Erector Spinae Plane Block for Improving Early Quality of Recovery After Transapical Transcatheter Aortic Valve Implantation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the effectiveness of dexmedetomidine (Dex) as an adjuvant for ropivacaine in a thoracic paravertebral block (TPVB) combined with an erector spinae plane block (ESPB) for improving early quality of recovery and postoperative pain after transapical transcatheter aortic valve implantation (TAVI).
Gui‐Ling Dong, Rong‐En Qiu, Chen‐Zhan Xu   +2 more
wiley   +1 more source

Accelerated signal propagation speed in human neocortical dendrites. [PDF]

Elife
Oláh G, Lákovics R, Shapira S, Leibner Y, Szücs A, Csajbók ÉA, Barzó P, Molnár G, Segev I, Tamás G.   +9 more
europepmc   +1 more source

Advances and Challenges in Pluripotent Stem Cell‐Based Whole‐Cell Vaccines for Cancer Treatment

Medicine Bulletin, EarlyView.
ABSTRACT In recent decades, an unexpected application of pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), as a novel source for whole‐cell vaccines (WCVs) against cancer has attracted attention in the field of tumor immunotherapy.
Guoyue Wan, Jian‐Dong Huang, Ren‐He Xu, Meiling Jin   +3 more
wiley   +1 more source