Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang +7 more
wiley +1 more source
Layer V Neocortical neurons from individuals With drug-resistant epilepsy show multiple synaptic alterations but lack somatic hyperexcitability. [PDF]
Márquez LA +8 more
europepmc +1 more source
Non-Decaying postsynaptics potentials and delayed spikes in hippocampal pyramidal neurons generated by a zero slope conductance created by the persistent Na+ current [PDF]
César C. Ceballos +3 more
openalex +1 more source
Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi +10 more
wiley +1 more source
Non-Hebbian Synaptic Plasticity Induced by Repetitive Postsynaptic Action Potentials [PDF]
Hiroyuki Kato +2 more
openalex +1 more source
New opportunities for bioscaffold‐enabled spinal cord injury repair
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi +11 more
wiley +1 more source
Propofol regulates arousal by enhancing inhibitory synaptic transmission of noradrenergic neurons in the locus coeruleus of adult male mice. [PDF]
Abe T +7 more
europepmc +1 more source
GABAergic mechanisms of excitation and hypersynchrony in adult rat hippocampus [PDF]
Uusisaari, Marylka
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