Distribution of densin in neurons. [PDF]
PLoS ONE, 2018 Densin is a scaffold protein known to associate with key elements of neuronal signaling. The present study examines the distribution of densin at the ultrastructural level in order to reveal potential sites that can support specific interactions of ...
Ayse Dosemeci +3 more
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Loss of Presynaptic and Postsynaptic Structures Is Accompanied by Compensatory Increase in Action Potential-Dependent Synaptic Input to Layer V Neocortical Pyramidal Neurons in Aged Rats [PDF]
Journal of Neuroscience, 2000 Reduction in both presynaptic and postsynaptic structures in the aging neocortex may significantly affect functional synaptic properties in this area. To directly address this issue, we combined whole-cell patch-clamp recording of spontaneously occurring
Tak Pan Wong +5 more
openalex +2 more sources
Frontiers in Cellular Neuroscience, 2021 Noise exposure is particularly stressful to hair-cell mitochondria, which must produce enough energy to meet high metabolic demands as well as regulate local intracellular Ca2+ concentrations.
Melanie Holmgren +2 more
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Analysis of the slow excitatory postsynaptic potential in bullfrog sympathetic ganglion cells.
The Japanese Journal of Physiology, 1976 The ionic mechanism of the slow excitatory postsynaptic potential (slow EPSP), i.e. the muscarinic action of acetylcholine (ACh), was studied either by stimulating preganglionic nerves or by applying ACh in curarized sympathetic ganglion cells of ...
Kenji Kuba, Kyozo Koketsu
semanticscholar +1 more source
Functional maps of neocortical local circuitry
Frontiers in Neuroscience, 2007 This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
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Modeling Calcium Dynamics and Inhibition Based Synaptic Plasticity in Dendritic Spines
Mathematical Modelling and Analysis, 2014 Inhibitory synapses through GABAergic channels not only change spine's calcium dynamics but also modulate postsynaptic current mediated through glutamate receptors.
Muhammad Dur-e-Ahmad
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Mouse-derived Synaptosomes Trypsin Cleavage Assay to Characterize Synaptic Protein Sub-localization. [PDF]
Bio ProtocNeurons communicate through neurotransmission at highly specialized junctions called synapses. Each neuron forms numerous synaptic connections, consisting of presynaptic and postsynaptic terminals.
Shergill JK, Tehran DA.
europepmc +2 more sources
Postsynaptic GABA(B) Receptors Contribute to the Termination of Giant Depolarizing Potentials in CA3 Neonatal Rat Hippocampus [PDF]
Frontiers in Cellular Neuroscience, 2017 During development, hippocampal CA3 network generates recurrent population bursts, so-called Giant Depolarizing Potentials (GDPs). GDPs are characterized by synchronous depolarization and firing of CA3 pyramidal cells followed by afterhyperpolarization ...
Ilgam Khalilov +4 more
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Brain Dystrophin in Duchenne Dystrophy
Pediatric Neurology Briefs, 1995 To define the potential pathogenic role of dystrophin deficiency in the cognitive impairment characteristic of Duchenne muscular dystrophy (DMD), the protein in brain cortical synapses of an 8-year-old patient examined at autopsy and an age-matched ...
J Gordon Millichap
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Retrograde Synaptic Signaling Mediated by K+ Efflux through Postsynaptic NMDA Receptors
Cell Reports, 2013 Synaptic NMDA receptors (NMDARs) carry inward Ca2+ current responsible for postsynaptic signaling and plasticity in dendritic spines. Whether the concurrent K+ efflux through the same receptors into the synaptic cleft has a physiological role is not ...
Pei-Yu Shih +7 more
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