Results 81 to 90 of about 10,231,702 (322)

Differential role of pre- and postsynaptic neurons in the activity-dependent control of synaptic strengths across dendrites.

open access: yesPLoS Biology, 2019
Neurons receive a large number of active synaptic inputs from their many presynaptic partners across their dendritic tree. However, little is known about how the strengths of individual synapses are controlled in balance with other synapses to ...
Mathieu Letellier   +3 more
doaj   +1 more source

Reinforcement learning in populations of spiking neurons [PDF]

open access: yes, 2008
Population coding is widely regarded as a key mechanism for achieving reliable behavioral responses in the face of neuronal variability. But in standard reinforcement learning a flip-side becomes apparent.
A Pouget   +13 more
core   +2 more sources

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Molecular and structural bases for postsynaptic signal processing: interaction between postsynaptic density and postsynaptic membrane rafts

open access: yesJournal of Neurorestoratology, 2013
Tatsuo Suzuki,1 Wei-Dong Yao21Department of Neuroplasticity, Shinshu University Graduate School of Medicine, Matsumoto, Japan; 2Department of Psychiatry, Beth Israel Deaconess Medical Center, and Division of Neuroscience, New England Primate Research ...
Suzuki T, Yao WD
doaj  

Identification of proteins in the postsynaptic density fraction by mass spectrometry [PDF]

open access: yes, 2000
Our understanding of the organization of postsynaptic signaling systems at excitatory synapses has been aided by the identification of proteins in the postsynaptic density (PSD) fraction, a subcellular fraction enriched in structures with the morphology ...
Jensen, Ole N.   +5 more
core   +2 more sources

Organic Ferroelectric Synaptic Transistors for Neural Image Recognition Networks

open access: yesAdvanced Materials Interfaces, EarlyView.
All organic transistors, where both the dielectric and semiconducting layers are polymeric, are developed as electrical synaptic devices. Two copolymers of PVDF as the dielectric layer with large differences in their saturation polarizability and memory window are chosen.
Evan Restuccia   +2 more
wiley   +1 more source

Spindle oscillations are generated in the dorsal thalamus and modulated by the thalamic reticular nucleus [PDF]

open access: yes, 2008
Spindle waves occur during the early stage of slow wave sleep and are thought to arise in the thalamic reticular nucleus (TRN), causing inhibitory postsynaptic potential spindle-like oscillations in the dorsal thalamus that are propagated to the cortex ...
Chun-Hua Liu   +7 more
core   +1 more source

Stability of Negative Image Equilibria in Spike-Timing Dependent Plasticity

open access: yes, 2003
We investigate the stability of negative image equilibria in mean synaptic weight dynamics governed by spike-timing dependent plasticity (STDP). The neural architecture of the model is based on the electrosensory lateral line lobe (ELL) of mormyrid ...
Alan Williams   +29 more
core   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

open access: yesAdvanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu   +12 more
wiley   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

open access: yesAdvanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

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