Results 91 to 100 of about 3,141,750 (349)

K-ATP channel gene expression is induced by urocortin and mediates its cardioprotective effect [PDF]

, 2002
Background-Urocortin is a novel cardioprotective agent that can protect cardiac myocytes from the damaging effects of ischemia/reperfusion both in culture and in the intact heart and is effective when given at reperfusion.Methods and Results-We have ...
Chanalaris, A, Comini, L, Ferrari, R, Hubank, M, Knight, RA, Latchman, DS, Lawrence, KM, Pasini, E, Scarabelli, T, Stephanou, A, Tinker, A, Townsend, PA   +11 more
core  

Modulating Two‐Photon Absorption in a Pyrene‐Based MOF Series: An In‐Depth Investigation of Structure–Property Relationships

Advanced Functional Materials, EarlyView.
This study investigates H4TBAPy‐based metal–organic frameworks (MOFs) ‐ NU‐1000, NU‐901, SrTBAPy, and BaTBAPy ‐ for multiphoton absorption (MPA) performance. It observes topology‐dependent variations in the 2PA cross‐section, with BaTBAPy exhibiting the highest activity.
Simon N. Deger, Helmy Pacheco Hernandez, Yang Cui, Hongxing Hao, Vanessa Ramm, David C. Mayer, Khai‐Nghi Truong, Roland A. Fischer, Jürgen Hauer, Mariana Kozlowska, Alexander Pöthig   +10 more
wiley   +1 more source

KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus

Journal of Diabetes Research, 2015
Diabetes mellitus (DM) is a major worldwide health problem and its prevalence has been rapidly increasing in the last century. It is caused by defects in insulin secretion or insulin action or both, leading to hyperglycemia.
Polin Haghvirdizadeh, Zahurin Mohamed, Nor Azizan Abdullah, Pantea Haghvirdizadeh, Monir Sadat Haerian, Batoul Sadat Haerian   +5 more
doaj   +1 more source

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura, D’Amato, Andrea, Fedele, Francesco, Mancone, Massimo, Netti, Lucrezia, Palmirotta, Raffaele, Pucci, Mariateresa, Severino, Paolo, Volterrani, Maurizio   +8 more
core   +2 more sources

Highly Scalable, Raspberry‐Like Microbeads with Nano‐/Micro‐Confined Hybrid Hydrogel Desiccants for Rapid Atmospheric Water Harvesting

Advanced Functional Materials, EarlyView.
A scalable nano‐/micro‐confinement strategy is developed, where polyacrylamide (PAM)‐LiCl hybrid desiccants are confined within hollow nanoparticles (HNPs) and assembled into raspberry‐like microbeads. The beads have a hydrogel‐rich core and an NP‐rich shell for fast absorption and desorption, releasing water 13.6 L kg⁻¹ day⁻¹.
Yunchan Lee, So Hee Nah, Kun‐Yu Wang, Yinding Chi, Jong Bin Kim, Ziyun Zhang, Shu Yang   +6 more
wiley   +1 more source

Voltage-Gated Potassium Channel Kv1.3 as a Target in Therapy of Cancer

Frontiers in Oncology, 2019
Voltage-gated potassium channel Kv1.3 is an integral membrane protein, which is selectively permeable for potassium ions and is activated upon a change of membrane potential.
Andrzej Teisseyre, Anna Palko-Labuz, Kamila Sroda-Pomianek, Krystyna Michalak   +3 more
doaj   +1 more source

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family*

Journal of Biological Chemistry, 2012
Background: The potassium channel inhibitory activity of scorpion Kunitz-type toxins has not yet been determined. Results: We identified the first scorpion Kunitz-type potassium channel toxin family with three groups and seven members.
Zong-yun Chen, Youtian Hu, Weishan Yang, Yawen He, Jing Feng, Bin Wang, Rui Zhao, Jiu-ping Ding, Z. Cao, Wenxin Li, Yingliang Wu   +10 more
semanticscholar   +1 more source

MiRP2 forms potassium channels in skeletal muscle with Kv3.4 and is associated with periodic paralysis. [PDF]

, 2001
The subthreshold, voltage-gated potassium channel of skeletal muscle is shown to contain MinK-related peptide 2 (MiRP2) and the pore-forming subunit Kv3.4.
Abbott, GW, Bendahhou, S, Butler, MH, Dalakas, MC, Goldstein, SA, Ptacek, LJ   +5 more
core  

Metal‐Organic Framework Embedded Electrospun Fibrous Membranes‐Based Hybrid Nanogenerators with Hierarchical Modified Polyamide Films for Mechanical Energy Harvesting and IoT Applications

Advanced Functional Materials, EarlyView.
Hybrid nanogenerator (HNG) based on a zinc‐metal‐organic framework‐loaded fibrous film integrated with a hierarchically modified nylon film having micropatterns and micropores is fabricated via an electrospinning technique, and its electrical properties are optimized. The HNGs are incorporated into wearable garments and automobile systems for practical
Sontyana Adonijah Graham, Anand Kurakula, Venkata Siva Kavarthapu, Jun Kyu Lee, Punnarao Manchi, Mandar Vasant Paranjape, Jae Su Yu   +6 more
wiley   +1 more source

Effects of Sodium Azide, Barium Ion, d-Amphetamine and Procaine on Inward Rectifying Potassium Channel 6.2 Expressed in Xenopus Oocytes

Journal of the Formosan Medical Association, 2008
Background/Purpose: Inward rectifying potassium channel 6.2 (Kir6.2 Δ C26 channel) is closely related to ATP-sensitive potassium channels. Whether sodium azide, barium ion, d-amphetamine or procaine acts directly on the Kir6.2 Δ C26 channel remains ...
Fan-Lu Kung, Jung-Lung Tsai, Chien-Hsing Lee, Kuo-Long Lou, Chih-Yung Tang, Horng-Huei Liou, Kuan-Ling Lu, Yi-Hung Chen, Wun-Jheng Wang, Ming-Cheng Tsai   +9 more
doaj   +1 more source