Results 101 to 110 of about 3,141,750 (349)

Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175

open access: yeseLife, 2020
Transmembrane protein 175 (TMEM175) is a K+-selective ion channel expressed in lysosomal membranes, where it establishes a membrane potential essential for lysosomal function and its dysregulation is associated with the development of Parkinson’s Disease.
SeCheol Oh   +2 more
doaj   +1 more source

Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries

open access: yesEuropean Respiratory Journal, 2012
The potassium channel TWIK-related acid sensitive potassium (TASK)-1 channel, together with other potassium channels, controls the low resting tone of pulmonary arteries.
C. Nagaraj   +10 more
semanticscholar   +1 more source

MinK residues line a potassium channel pore. [PDF]

open access: yes, 1996
MinK has neither the P region nor signature sequence that characterizes pore-forming subunits of all known K+ channels. A specific minK region has now been identified that affects external blockade by 2 common probes of K+ channel pores.
Goldstein, SA, Tai, KK, Wang, KW
core  

A Universal Way to Manipulate Droplet via Light‐Fueled Thermocapillary Convection

open access: yesAdvanced Functional Materials, EarlyView.
A non‐contact light‐induced droplet manipulation strategy fueled by mid‐infrared (MIR) light irradiation is introduced. No additional additives and/or complex substrate are required. Here, thermocapillary convection, directly generated by temperature gradient at outer surface of droplet via localized surface heating, plays a key role to propel the ...
Hyesun Hwang   +5 more
wiley   +1 more source

The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception

open access: yesCell Reports, 2018
Summary: Inhibition of nociceptor activity is important for the prevention of spontaneous pain and hyperalgesia. To identify the critical K+ channels that regulate nociceptor excitability, we performed a forward genetic screen using a Drosophila larval ...
Kia C.E. Walcott   +4 more
doaj   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

open access: yesAdvanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran   +11 more
wiley   +1 more source

Inactivation in the potassium channel KcsA

open access: yesJournal of Structural Biology: X, 2019
Inactivation, the slow cessation of transmission after activation, is a general feature of potassium channels. It is essential for their function, and malfunctions in inactivation leads to numerous pathologies.
Yunyao Xu, Ann E. McDermott
doaj   +1 more source

Cu2O/Cu Chiral Catalysts for Highly Selective Solar‐Assisted CO2‐to‐CO Electroreduction

open access: yesAdvanced Functional Materials, EarlyView.
To address the poor target‐product selectivity of the eCO2RR, breakthrough approaches based on the chiral‐induced spin selectivity phenomenon enhance the Faradaic efficiency (FE) for target hydrocarbons, such as CO. To induce this spin polarization strategy in Cu2O/Cu catalysts, it is proposed using amine‐based intermediate organic molecules with ...
Hyungsoo Lee   +13 more
wiley   +1 more source

Nicorandil-Induced Hyperkalemia in a Uremic Patient

open access: yesCase Reports in Medicine, 2012
Nicorandil is an antianginal agent with nitrate-like and ATP-sensitive potassium channel activator properties. After activation of potassium channels, potassium ions are expelled out of the cells, which lead to membrane hyperpolarization, closure of ...
Hung-Hao Lee   +4 more
doaj   +1 more source

Neuroprotective effects of potassium channel openers on cerebral ischemia–reperfusion injury in diabetic rats

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2017
Objectives: This study was done to estimate the potential neuroprotective role of potassium channel openers in cerebral ischemia–reperfusion (IR) injury in streptozotocin (STZ) induced type-I diabetic rats (T1DR).
Anand B. Pithadia   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy