Results 111 to 120 of about 444,617 (369)
Journal of the Formosan Medical Association, 2008 Background/Purpose: Inward rectifying potassium channel 6.2 (Kir6.2 Δ C26 channel) is closely related to ATP-sensitive potassium channels. Whether sodium azide, barium ion, d-amphetamine or procaine acts directly on the Kir6.2 Δ C26 channel remains ...
Fan-Lu Kung +9 more
doaj +1 more source
Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
eLife, 2020 Transmembrane protein 175 (TMEM175) is a K+-selective ion channel expressed in lysosomal membranes, where it establishes a membrane potential essential for lysosomal function and its dysregulation is associated with the development of Parkinson’s Disease.
SeCheol Oh +2 more
doaj +1 more source
Strontium and Barium in Aqueous Solution and a Potassium Channel Binding Site [PDF]
, 2018 Ion hydration structure and free energy establish criteria for understanding selective ion binding in potassium K+ ion channels, and may be significant to understanding blocking mechanisms as well. Recently, we investigated the hydration properties of Ba2+, the most potent blocker of K+ channels among the simple metal ions.
arxiv +1 more source
Characterization of potassium channels in pancreatic β cells from ob/ob mice [PDF]
, 1990 The patch-clamp technique in the cell-attached mode was used to study the K channels present in the membrane of cultured pancreatic β cells from ob/ob mice. Three types of K+ channels were regularly observed, with conductances of 64, 20 and 146 pS.
Atwater, Illani +2 more
core +1 more source
Advanced Functional Materials, EarlyView.A novel stratum corneum‐inspired zwitterionic hydrogel is developed for intelligent, flexible sensors, featuring intrinsic water retention and anti‐freezing properties. The quasi‐gel, composed of hygroscopic polymers and bound water, maintains its softness across a wide range of humidity.
Meng Wu +8 more
wiley +1 more source
Bulletin of Faculty of Pharmacy Cairo University, 2017 Objectives: This study was done to estimate the potential neuroprotective role of potassium channel openers in cerebral ischemia–reperfusion (IR) injury in streptozotocin (STZ) induced type-I diabetic rats (T1DR).
Anand B. Pithadia +2 more
doaj +1 more source
Electrodiffusion with calcium-activated potassium channels in dendritic spine [PDF]
arXiv, 2019 We investigate calcium signaling feedback through calcium-activated potassium channels of a dendritic spine by applying the immersed boundary method with electrodiffusion. We simulate the stochastic gating of such ion channels and the resulting spatial distribution of concentration, current, and membrane voltage within the dendritic spine.
arxiv
Selection of medication in hospitalised elderly patients with Angina Pectoris [PDF]
, 2004 Objective: To evaluate medication changes in hospitalised elderly patients diagnosed with angina pectoris and to compare the selection of medication with evidence-based treatment guidelines. Design: Review of medical notes and patient interview. Setting:
Cacciottolo, Joseph M. +2 more
core
Advanced Functional Materials, EarlyView.A novel polymer electrolyte membrane with a hyperbranched interpenetrating hydrogen bond network structure is developed. The unique structure of the hyperbranched polymer contributes to a high glass transition temperature exceeding 400 °C, enabling its operation at elevated temperatures for fuel cell applications.
Lingping Zeng +10 more
wiley +1 more source
Evolutionary Analysis of Biological Excitability [PDF]
arXiv, 2006 Excitability is an attribute of life, and is a driving force in the descent of complexity. Cellular electrical activity as realized by membrane proteins that act as either channels or transporters is the basis of excitability. Electrical signaling is mediated by a wave of action potentials, which consist of synchronous redistribution of ionic gradients
arxiv