Results 111 to 120 of about 3,016,110 (399)

Effects of Sodium Azide, Barium Ion, d-Amphetamine and Procaine on Inward Rectifying Potassium Channel 6.2 Expressed in Xenopus Oocytes

Journal of the Formosan Medical Association, 2008
Background/Purpose: Inward rectifying potassium channel 6.2 (Kir6.2 Δ C26 channel) is closely related to ATP-sensitive potassium channels. Whether sodium azide, barium ion, d-amphetamine or procaine acts directly on the Kir6.2 Δ C26 channel remains ...
Fan-Lu Kung, Jung-Lung Tsai, Chien-Hsing Lee, Kuo-Long Lou, Chih-Yung Tang, Horng-Huei Liou, Kuan-Ling Lu, Yi-Hung Chen, Wun-Jheng Wang, Ming-Cheng Tsai   +9 more
doaj   +1 more source

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family*

Journal of Biological Chemistry, 2012
Background: The potassium channel inhibitory activity of scorpion Kunitz-type toxins has not yet been determined. Results: We identified the first scorpion Kunitz-type potassium channel toxin family with three groups and seven members.
Zong-yun Chen, Youtian Hu, Weishan Yang, Yawen He, Jing Feng, Bin Wang, Rui Zhao, Jiu-ping Ding, Z. Cao, Wenxin Li, Yingliang Wu   +10 more
semanticscholar   +1 more source

Vat Photopolymerization of High Molecular Weight Polymer Latexes with Pseudothermoplastic Properties for Recyclability

Advanced Functional Materials, EarlyView.
A photocurable latex system enables high‐resolution vat photopolymerization of water‐dispersed thermoplastics, yielding pseudothermoplastic materials with recyclability. The formulation permits precise control over mechanical properties and supports reprocessing through conventional and extrusion‐based methods. Compatibility with two‐photon 3D printing
Jon Ayestaran, Xabier Lopez de Pariza, Fernando Vidal, Clara Vazquez‐Martel, Alodi Pascal, Siwei Yu, Miren Aguirre, Alshakim Nelson, Jose R. Leiza, Eva Blasco, Timothy E. Long, Robert Aguirresarobe, Haritz Sardon   +12 more
wiley   +1 more source

Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels [PDF]

, 2018
Drugs do not act solely by canonical ligand–receptor binding interactions. Amphiphilic drugs partition into membranes, thereby perturbing bulk lipid bilayer properties and possibly altering the function of membrane proteins.
Aldrich, Richard W., Andersen, Olaf S., Dockendorff, Chris, Dodge, Matthew W., Eum, Kenneth S., Gandhi, Disha M., Ingolfsson, Helgi I., Kapoor, Ruchi, Kimball, Ian H., Martin, Stephen F., Peyear, Thasin, Rusinova, Radda, Sack, Jon T.   +12 more
core   +2 more sources

Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries

European Respiratory Journal, 2012
The potassium channel TWIK-related acid sensitive potassium (TASK)-1 channel, together with other potassium channels, controls the low resting tone of pulmonary arteries.
C. Nagaraj, B. Tang, Z. Bálint, M. Wygrecka, A. Hrzenjak, G. Kwapiszewska, E. Stacher, J. Lindenmann, E. Weir, H. Olschewski, A. Olschewski   +10 more
semanticscholar   +1 more source

Ultrasoft Iontronics: Stretchable Diodes Enabled by Ionically Conductive Bottlebrush Elastomers

Advanced Functional Materials, EarlyView.
This work introduces a solvent‐free, ultrasoft, and stretchable ionic diode based on oppositely charged bottlebrush elastomers (BBEs). The BBE diode exhibits an ultralow Young's modulus (<23 kPa), a high rectification ratio of 46, and stretchability over 400%.
Xia Wu, Pengfei Xu, Zefang Zhang, Qi Yang, Xi Huang, Peng Pan, Xinyu Liu   +6 more
wiley   +1 more source

Neuroprotective effects of potassium channel openers on cerebral ischemia–reperfusion injury in diabetic rats

Bulletin of Faculty of Pharmacy Cairo University, 2017
Objectives: This study was done to estimate the potential neuroprotective role of potassium channel openers in cerebral ischemia–reperfusion (IR) injury in streptozotocin (STZ) induced type-I diabetic rats (T1DR).
Anand B. Pithadia, Shital S. Panchal, Denvanshu J. Patel   +2 more
doaj   +1 more source

The delayed rectifier potassium conductance in the sarcolemma and the transverse tubular system membranes of mammalian skeletal muscle fibers. [PDF]

, 2012
A two-microelectrode voltage clamp and optical measurements of membrane potential changes at the transverse tubular system (TTS) were used to characterize delayed rectifier K currents (IK(V)) in murine muscle fibers stained with the potentiometric dye di-
DiFranco, Marino, Quinonez, Marbella, Vergara, Julio L   +2 more
core   +1 more source

Pharmacology of Cardiac Potassium Channels [PDF]

, 2010
Cardiac K(+) channels are cardiomyocyte membrane proteins that regulate K(+) ion flow across the cell membrane on the electrochemical gradient and determine the resting membrane potential and the cardiac action potential morphology and duration. Several K(+) channels have been well studied in the human heart.
Li, GR, Dong, MQ
openaire   +5 more sources

A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring

Advanced Functional Materials, EarlyView.
This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee, Jieun Jung, Hyeongoh Park, Dongwuk Jung, Doyune Kim, Changeui Hong, Seungbeom Kang, Hyunsoo Kim, Tae Kim, Jongho Lee   +9 more
wiley   +1 more source