Results 11 to 20 of about 3,177,241 (350)
Human sperm ion channel (dys)function:implications for fertilization [PDF]
, 2019 BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R. +3 more
core +4 more sources
Nature Communications, 2019 Potassium channels are presumed to have two allosterically coupled gates, the activation gate and the selectivity filter gate, that control channel opening, closing, and inactivation.
Wojciech Kopec +2 more
semanticscholar +1 more source
The conduction pathway of potassium channels is water free under physiological conditions. [PDF]
, 2019 Ion conduction through potassium channels is a fundamental process of life. On the basis of crystallographic data, it was originally proposed that potassium ions and water molecules are transported through the selectivity filter in an alternating ...
Chevelkov, V. +9 more
core +1 more source
Identification of an ATP-sensitive potassium channel in mitochondria
Nature, 2019 Mitochondria provide chemical energy for endoergonic reactions in the form of ATP, and their activity must meet cellular energy requirements, but the mechanisms that link organelle performance to ATP levels are poorly understood.
Angela Paggio +8 more
semanticscholar +1 more source
Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]
, 2004 The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C +17 more
core +2 more sources
Epilepsy Gene Therapy Using an Engineered Potassium Channel
Journal of Neuroscience, 2019 Refractory focal epilepsy is a devastating disease for which there is frequently no effective treatment. Gene therapy represents a promising alternative, but treating epilepsy in this way involves irreversible changes to brain tissue, so vector design ...
A. Snowball +12 more
semanticscholar +1 more source
Voltage-Gated Potassium Channel Kv1.3 as a Target in Therapy of Cancer
Frontiers in Oncology, 2019 Voltage-gated potassium channel Kv1.3 is an integral membrane protein, which is selectively permeable for potassium ions and is activated upon a change of membrane potential.
A. Teisseyre +3 more
semanticscholar +1 more source
A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes [PDF]
, 2005 We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated potassium channels in modulating sensory transmission from peripheral afferents into the rat spinal cord.
Bahia, PK +7 more
core +1 more source
Pulmonary vasoconstrictor action of KCNQ potassium channel blockers [PDF]
, 2006 KCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important physiological functions. Recent reports indicate that KCNQ channels may also be expressed in portal vein where they are suggested to influence ...
AM Evans +23 more
core +3 more sources
Journal of Experimental Botany, 2016 Highlight Overexpression of the potassium channel OsAKT1 improves rice potassium nutrition and resilience to water stress.
I. Ahmad, A. Mian, F. Maathuis
semanticscholar +1 more source