N-Substituted-2-(9H-Xanthen-9-yl)acetamide Derivatives Induce In Vitro Colon Cancer Cell Death via TASK-1 Inhibition: Lead Compounds for Further Optimization as TASK-1-Targeted Therapeutics in Colorectal Cancer. [PDF]
Al Khzem AH +13 more
europepmc +1 more source
Potassium channel openers: effects on the vascular system
openaire +2 more sources
Achieving High‐Density and Stress‐Resilient Maize Breeding Via Germplasm Innovation
Global population growth and climate change have exacerbated the global food crisis. This perspective presents a conceptual framework focusing on enhancing population advantages. Several novel breeding objectives are proposed to improve density tolerance and stress resistance for yield improvement.
Xinlong Li +9 more
wiley +1 more source
Endothelial triple-pathway vasorelaxation as an adjunctive strategy in resistant hypertension. [PDF]
Madeddu P +3 more
europepmc +1 more source
Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart. [PDF]
Killeen MJ +6 more
europepmc +1 more source
Sustainable Synaptic Device with Two‐Dimensional Ferroelectric Materials for Neuromorphic Computing
α‐In2Se3 based FeSFETs can be utilized as sustainable devices through polarization switching governed by both out‐of‐plane and in‐plane polarizations. Upon reaching a fatigued state, current annealing enabled by conductance modulation can significantly enhance the endurance of FeSFETs.
Jaewook Yoo +12 more
wiley +1 more source
Voltage-gated potassium channels and genetic epilepsy. [PDF]
Zheng Y, Chen J.
europepmc +1 more source
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma +28 more
wiley +1 more source
Actions of Midostaurin as Cation Channel and Tyrosine Kinase Inhibitor in Diffuse Intrinsic Pontine Glioma Cell Lines. [PDF]
Antonacci M +7 more
europepmc +1 more source
Increasing nanocurvature effectively enriches the local electron density of the M–N4 motif, which facilitates electron transfer from the metal center to nitrogen atoms. This electronic behavior intensifies the localization and asymmetric distribution of charge, thereby significantly amplifying the dipole moment and polarizability.
Daohu Sheng +7 more
wiley +1 more source

