Results 101 to 110 of about 11,215 (198)

Potentiation of Opioid-Induced Analgesia by L-Type Calcium Channel Blockers: Need for Clinical Trial in Cancer Pain

Indian Journal of Anaesthesia, 2008
Previous reports indicate that the analgesic effect of opioids is due to both closure of specific voltage-gated calcium channels (N- and P/Q-types) and opening of G protein-coupled inwardly rectifying potassium channels (GIRKs) in neurons concerned with ...
S Basu Ray, Raj D Mehra
doaj  

Ligand transduction mechanisms of inwardly-rectifying potassium channels

, 2013
Regulation of inwardly-rectifying potassium (Kir) channels by intracellular ligands couples cell membrane excitability to important signaling cascades and metabolic pathways. Particularly, the ATP-sensitive potassium (KATP) channels, highly expressed in diverse excitable tissues, are the keystone components of glucose-stimulated insulin secretion in ...
openaire   +1 more source

Magnesium and Cardiac Arrythmias: An Overlooked Guardian of Electrical Stability. [PDF]

Cardiol Res
Jia K, Noguer JA, Rimsky ER, Pikale GS, Sattarzadeh A, Pradeep AG, Khayat O, Ahmad K, Vachss D, Zhang F, Pearce E, Khan S, El-Sayegh S.   +12 more
europepmc   +1 more source

Mechanism of Mutation in G Protein-Gated Inwardly Rectifying K⁺ Channel in Familial Hyperaldosteronism-Type III: Residue Fluctuations and Conformational Instability. [PDF]

Molecules
AbuMaziad AS, Liang JJ, Logothetis ANO, Pitsillou E, Hung A, Beck J, Zudekoff R, Hafezi A, Chy B, Slack A, Qannus A, El-Osta A, El-Osta A, Karagiannis TC.   +13 more
europepmc   +1 more source

KCNJ4 variants disrupt inward-rectifier potassium channel function and cause refractory epilepsy. [PDF]

Epilepsia
Pan H, Liu D, Xu W, Li Y, Hu J, Henry O, Fuchs A, Jamra RA, Liu Z, He M, Chen Y, Wu S, Dong X, Chen Y, Wang P, Gu W, Jing H, Tang Y, Wang YJ, Mao X, Xiao N.   +20 more
europepmc   +1 more source

Pathophysiology of homocysteine: insights into ion channel dysfunction. [PDF]

Pflugers Arch
Chmúrčiaková N, Stringer RN, Cmarko L, Filipova A, Lacinova L, Weiss N.   +5 more
europepmc   +1 more source

Paracrine inhibition via G protein inwardly rectifying potassium channels regulates glucagon secretion from human pancreatic alpha cells. [PDF]

Cell Rep
Panzer JK, Lang AL, Levi NJ, Garcia PA, Barro-Soria R, Caicedo A.   +5 more
europepmc   +1 more source

Novel Mutations in KCNJ10 Gene Associated With SeSAME Syndrome: Rare Disorder With Possible Common Mutation. [PDF]

Mol Genet Genomic Med
Shakeri S, Mohammadi S, Sadeghipour F, Masoudi M, Entezam M.   +4 more
europepmc   +1 more source

Prefrontal Cortex 5-HT1A Receptor-Coupled Inwardly Rectifying Potassium Channels Decreased Seizure Susceptibility in Rat Models With Autism Spectrum Disorder. [PDF]

Neural Plast
Li Z, Sun Y, Huo X, Ren X, Ding N, Qian X, Li A, Sun T.   +7 more
europepmc   +1 more source

KCNJ11 (p.Arg192Cys)-associated MODY13 with coexisting autoimmunity in a child, a case report. [PDF]

BMC Pediatr
Fatani TH.
europepmc   +1 more source