Results 41 to 50 of about 3,077,235 (395)

Role of potassium channels in female reproductive system [PDF]

open access: yesObstetrics & Gynecology Science, 2020
Potassium channels are widely expressed in most types of cells in living organisms and regulate the functions of a variety of organs, including kidneys, neurons, cardiovascular organs, and pancreas among others. However, the functional roles of potassium
Jun-Mo Kim   +3 more
doaj   +1 more source

Modeled channel distributions explain extracellular recordings from cultured neurons sealed to microelectrodes [PDF]

open access: yes, 2002
Amplitudes and shapes of extracellular recordings from single neurons cultured on a substrate embedded microelectrode depend not only on the volume conducting properties of the neuron-electrode interface, but might also depend on the distribution of ...
Buitenweg, Jan Reinoud   +2 more
core   +3 more sources

Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]

open access: yes, 2004
The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C   +17 more
core   +2 more sources

Potassium channels as drugs targets in therapy of cardiovascular diseases: 25 years later [PDF]

open access: yesSanamed, 2013
Potassium channels are the most variable ion channel group. They participate in numerous cardiovascular functions, for example regulation of vascular tone, maintenance of resting cardiac membrane potential and excitability of cardiac conduction tissue ...
Protić Dragana   +2 more
doaj   +2 more sources

Feshbach resonances in potassium Bose-Bose mixtures

open access: yes, 2018
We present a detailed study of the scattering properties of ultracold mixtures of bosonic potassium atoms. We locate 20 previously unobserved Feshbach resonances in isotopic 39K-41K mixtures.
Cabrera, C. R.   +5 more
core   +1 more source

Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels. [PDF]

open access: yes, 2000
A 2 P domain potassium channel expressed in eye, lung, and stomach, Kcnk8, has recently been identified. To initiate further biochemical and genetic studies of this channel, we assembled the murine Kcnk8 cDNA sequence, characterized the genomic structure
Bockenhauer, D   +4 more
core   +1 more source

Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]

open access: yes, 1988
We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Endocytic Regulation of Voltage-Dependent Potassium Channels in the Heart

open access: yesJournal of Pharmacological Sciences, 2012
Understanding the regulation of cardiac ion channels is critical for the prevention of arrhythmia caused by abnormal excitability. Ion channels can be regulated by a change in function (qualitative) and a change in number (quantitative).
Kuniaki Ishii, Ikuo Norota, Yutaro Obara
doaj   +1 more source

K2P channels and their protein partners. [PDF]

open access: yes, 2005
A decade since their discovery, the K2P channels are recognized as pathways dedicated to regulated background leakage of potassium ions that serve to control neuronal excitability. The recent identification of protein partners that directly interact with
Goldstein, Steve AN   +2 more
core   +1 more source

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