Results 151 to 160 of about 686 (166)

Genomic insights into linezolid-resistant Enterococci revealed its evolutionary diversity and poxtA copy number heterogeneity

International Journal of Antimicrobial Agents, 2023
This study aimed to determine the molecular mechanisms of linezolid-resistant enterococci (LRE) in swine slaughterhouses in China and apply the "One Health" perspective to analyse the evolutionary dynamics of poxtA-positive E. faecium in clinical and non-clinical settings worldwide.The phenotypic and genomic characteristics of multiple LRE isolates ...
Qiaojun Wang, Kai Peng, Ziyi Liu, Yan Li, Xia Xiao, Xiang-Dang Du, Ruichao Li, Zhiqiang Wang   +7 more
openaire   +2 more sources

Clonal spread and horizontal transfer mediate dissemination of phenicol-oxazolidinone-tetracycline resistance gene poxtA in enterococci isolates from a swine farm in China

Veterinary Microbiology, 2021
The emergence of the phenicol-oxazolidinone-tetracycline resistance gene poxtA becomes a significant challenge for public health, since it confers a decreased susceptibility not only to the last resort drug linezolid, but also to florfenicol and doxycycline widely used in veterinary medicine.
Chang-Wei Lei, Xuan Chen, Si-Yi Liu, Tian-Yi Li, Yanpeng Chen, Hong-Ning Wang   +5 more
openaire   +2 more sources

Development of a multiplex-PCR to simultaneously detect acquired linezolid resistance genes cfr, optrA and poxtA in enterococci of clinical origin

Journal of Microbiological Methods, 2019
Linezolid-resistant enterococcus spp. are increasingly recognized by diagnostic laboratories. Resistance can be mediated by the expression of cfr, optrA or poxtA. We developed a multiplex-PCR to simultaneously detect all three genes. The PCR is suitable for microbiological diagnostics in order to restrict further spread of resistances in enterococci.
Jennifer K, Bender, Carola, Fleige, Ingo, Klare, Guido, Werner   +3 more
openaire   +2 more sources

Identification of an Enterococcus faecium strain isolated from raw bovine milk co-harbouring the oxazolidinone resistance genes optrA and poxtA in China

Veterinary Microbiology
Oxazolidinones are potent antimicrobial agents used to treat human infections caused by multidrug-resistant Gram-positive bacteria. The growing resistance to oxazolidinones poses a significant threat to public health. In August 2021, a linezolid-resistant Enterococcus faecium BN83 was isolated from a raw milk sample of cow in Inner Mongolia, China ...
Jie, Hou, Qiu, Xu, Longyu, Zhou, Jiyun, Chai, Longhua, Lin, Caiping, Ma, Yao, Zhu, Wanjiang, Zhang   +7 more
openaire   +2 more sources

Detection of poxtA2, a Presumptive poxtA Ancestor, in a Plasmid from a Linezolid-Resistant Enterococcus gallinarum Isolate.

Antimicrobial Agents and Chemotherapy, 2021
Alessandro Bartoloni, Ilaria Baccani, Marco Coppi   +2 more
exaly  

Identification of the Multiresistance Gene poxtA in Oxazolidinone-Susceptible Staphylococcus haemolyticus and Staphylococcus saprophyticus of Pig and Feed Origins

Pathogens, 2021
Zhenling Zeng
exaly  

Detection of an Enterococcus faecium Carrying a Double Copy of the PoxtA Gene from Freshwater River, Italy

Antibiotics, 2022
Andrea Brenciani, Eleonora Giovanetti, Gianluca Morroni   +2 more
exaly  

Genetic Context of optrA and poxtA in Florfenicol-Resistant Enterococci Isolated from Flowing Surface Water in Switzerland.

Antimicrobial Agents and Chemotherapy, 2021
Michael Biggel, Magdalena Nüesch-Inderbinen, Marc J A Stevens   +2 more
exaly  

Detection of the Phenicol–Oxazolidinone Resistance Gene poxtA in Enterococcus faecium and Enterococcus faecalis from Food-Producing Animals during 2008–2018 in Korea

Microorganisms, 2020
Suk-Kyung Lim, Seok Hyeon Na, Yoon Seek Yoon   +2 more
exaly  

Genetic features of the poxtA linezolid resistance gene in human enterococci from France

Journal of Antimicrobial Chemotherapy, 2021
Mohamed Sassi, Vincent Cattoir, Asma Zouari   +2 more
exaly