Results 161 to 170 of about 832 (175)

Molecular characterisation of linezolid- and vancomycin-resistant enterococci from healthy chicken in Tunisia [PDF]

open access: yes
Carmen Torres [0000-0003-3709-1690]   +6 more
core  

Genomic insights into linezolid-resistant Enterococci revealed its evolutionary diversity and poxtA copy number heterogeneity

International Journal of Antimicrobial Agents, 2023
This study aimed to determine the molecular mechanisms of linezolid-resistant enterococci (LRE) in swine slaughterhouses in China and apply the "One Health" perspective to analyse the evolutionary dynamics of poxtA-positive E. faecium in clinical and non-clinical settings worldwide.The phenotypic and genomic characteristics of multiple LRE isolates ...
Qiaojun Wang   +7 more
openaire   +2 more sources

Genetic Context of optrA and poxtA in Florfenicol-Resistant Enterococci Isolated from Flowing Surface Water in Switzerland

Antimicrobial Agents and Chemotherapy, 2021
Linezolid is an important last-resort antibiotic for the treatment of multidrug-resistant enterococci. The aim of this study was to further characterize the genetic context of optrA and poxtA in 10 florfenicol-resistant enterococci isolated from flowing surface water. In most genomes,
Biggel, Michael   +4 more
openaire   +3 more sources

Interregional spread in Spain of linezolid-resistant Enterococcus spp. isolates carrying the optrA and poxtA genes

International Journal of Antimicrobial Agents, 2020
The emergence of linezolid-resistant Enterococcus spp. (LRE) due to transferable resistance determinants is a matter of concern. To understand the contribution of the plasmid-encoded optrA and poxtA genes to the emergence of LRE, clinical isolates from different Spanish hospitals submitted to the Spanish Reference Laboratory from 2015-2018 were ...
Zaira Moure   +11 more
openaire   +2 more sources

Clonal spread and horizontal transfer mediate dissemination of phenicol-oxazolidinone-tetracycline resistance gene poxtA in enterococci isolates from a swine farm in China

Veterinary Microbiology, 2021
The emergence of the phenicol-oxazolidinone-tetracycline resistance gene poxtA becomes a significant challenge for public health, since it confers a decreased susceptibility not only to the last resort drug linezolid, but also to florfenicol and doxycycline widely used in veterinary medicine.
Chang-Wei Lei   +5 more
openaire   +2 more sources

Identification of plasmids co-carrying cfr(D)/optrA and cfr(D2)/poxtA linezolid resistance genes in two Enterococcus avium isolates from swine brain

Veterinary Microbiology, 2023
Oxazolidinones are critically important antibiotics to treat human infections caused by multidrug-resistant bacteria, therefore the occurrence of linezolid-resistant enterococci from food-producing animals poses a serious risk to human health. In this study, Enterococcus avium 38157 and 44917 strains, isolated from the brain of two unrelated piglets ...
Sonia Nina Coccitto   +10 more
openaire   +2 more sources

poxtA amplification and mutations in 23S rRNA confer enhanced linezolid resistance in Enterococcus faecalis

Journal of Antimicrobial Chemotherapy
Abstract Objectives This study aimed to explore the evolutionary patterns and resistance mechanisms of an Enterococcus faecalis strain harbouring poxtA under linezolid exposure. Methods A poxtA-carrying E. faecalis electrotransformant
Xinxin Shan   +9 more
openaire   +2 more sources

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