Results 51 to 60 of about 9,909 (229)

An mRNA Vaccine Based on Antigens From Conserved Regions of Monkeypox Virus A35R and M1R With a Dimer‐Like Conformation Confers Protection Against Both Monkeypox Virus and Vaccinia Virus Infections in Mice

MedComm, Volume 7, Issue 2, February 2026.
We developed four candidate mRNA vaccine antigens based on conserved sequences of MPXV A35R and M1R proteins. Our findings demonstrate that the MV2 vaccine possesses favorable immunogenicity and prophylactic potential against MPXV and VACV infections, positioning it as a promising clinical candidate for MPXV prevention.
Cong Tang, Longhai Yuan, Yun Xie, Yun Yang, Yanan Zhou, Junbing Wang, Hao Yang, Rui Peng, Jiali Xu, Wenhai Yu, Qing Huang, Wenqi Quan, Baisheng Li, Youchun Wang, Shuaiyao Lu   +14 more
wiley   +1 more source

Urinary virome perturbations in kidney transplantation [PDF]

, 2018
The human microbiome is important for health and plays a role in essential metabolic functions and protection from certain pathogens. Conversely, dysbiosis of the microbiome is seen in the context of various diseases. Recent studies have highlighted that
Carrie D. Nicora, Kristin Burnum-Johnson, Minnie M. Sarwal, Neil Mercer, Sharvin Nandoe, Sharvin Nandoe, Tara K. Sigdel, Wei-Jun Qian   +7 more
core   +5 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics

MedComm, Volume 7, Issue 1, January 2026.
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan, Yaqin Sun, Guangyan Sun, Cheng Niu, Xinyuan Zhao, Ming Zhao, Tongyao Liu, Suyue Zhang, Hui Zhai, Ankang Liu, Shouzhi Yu, Shuyuan Pan, Wu Zhong, Yuntao Zhang, Song Li   +14 more
wiley   +1 more source

First Molecular Characterisation of the Lumpy Skin Disease Virus From the North African Region, Algeria and Tunisia

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Highlights • Molecular characterisation of the LSDV in Algeria and Tunisia. PCR detection of the presence of the LSDV in 77.9% of the samples collected. • Cattle skin and nasal and buccal swabs were the most virulent material. • Phylogenetic analysis using the p32 gene revealed 100% sequence identity and grouping with GenBank‐published LSDV sequences ...
Ilhem Zouyed, Hichem Soualah, Samir Djemai, Ahmed Messai, Mohammed El Hadi Daia, Amir Mansour, Ines Hammami, Marwen Nouasri, Nabil Trifi, Médiha Khamassi Khbou   +9 more
wiley   +1 more source

Monkeypox outbreak in the post-eradication era of smallpox

The Egyptian Journal of Internal Medicine, 2023
Human monkeypox (MPOX) which recently hit the headlines is a rare, emerging zoonotic disease, only next to smallpox yet never attended adequately to halt the epidemic outbreak threat.
Naga Vishnu Kandra, Anjaly Mary Varghese, Praveen Kumar Uppala, Upendrarao Uttaravelli, Butti Lavanya, S. K. M. Shabana, Venkata Saibaba Somarouthu, Murali Krishna Balijepalli   +7 more
doaj   +1 more source

Polymerase chain reaction detection of avipox and avian papillomavirus in naturally infected wild birds: comparisons of blood, swab and tissue samples [PDF]

, 2014
Avian poxvirus (avipox) is widely reported from avian species, causing cutaneous or mucosal lesions. Mortality rates of up to 100% are recorded in some hosts. Three major avipox clades are recognized.
Buller R., Clara Escudero Duch, Hansen W., Howley P., Javier Pérez-Tris, Laura Benítez, Richard A. J. Williams, Saijo M., Sambrook J., Tripathy D.   +9 more
core   +3 more sources

Global Warming Affects the Pathogenesis of Important Fish Diseases in European Aquaculture

Reviews in Aquaculture, Volume 18, Issue 1, January 2026.
The effect of global warming on pathogens and their fish hosts that could exacerbate the negative outcomes for aquaculture. Changes in farming practices and the development of innovative mitigation tools may prove essential to cope with the effects and impacts of rising water temperatures on fish diseases in Europe.
George Rigos, Francesc Padrós, Maria Constenla, Ana Jerončić, Dimitra Kogiannou, Sofia Consuegra, Mikolaj Adamek, Ivona Mladineo   +7 more
wiley   +1 more source

Morphologic Differentiation of Viruses beyond the Family Level

Viruses, 2014
Electron microscopy has been instrumental in the identification of viruses by being able to characterize a virus to the family level. There are a few cases where morphologic or morphogenesis factors can be used to differentiate further, to the genus ...
Cynthia S. Goldsmith
doaj   +1 more source

The Impact of Monkeypox Virus Infection on Pregnancy Outcome: Clinical Features and Potential Pathogenic Mechanisms

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Monkeypox has garnered significant attention following its emergence in multiple countries and its designation as a global health emergency in 2022. There is a notable deficiency in clinical and experimental data regarding pregnancy outcomes following monkeypox infection.
Jingyi Wu, Fangbin Huang, Qingliang Zheng, Poorani Gurumallesh   +3 more
wiley   +1 more source

Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Life, 2023
Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects.
Faheem Anwar, Fatima Haider, Sarmir Khan, Ibrar Ahmad, Naveed Ahmed, Muhammad Imran, Summya Rashid, Zhi-Guang Ren, Saadullah Khattak, Xin-Ying Ji   +9 more
doaj   +1 more source