Results 11 to 20 of about 5,414 (165)

Cross-Protection of an Inactivated and a Live-Attenuated Lumpy Skin Disease Virus Vaccine against Sheeppox Virus Infections in Sheep [PDF]

Vaccines, 2023
Sheeppox virus (SPPV) (genus Capripoxvirus, family Poxviridae) infections are a highly virulent and contagious disease of sheep with a high morbidity and mortality, especially in naïve populations and young animals.
Janika Wolff, Martin Beer, Bernd Hoffmann   +2 more
doaj   +2 more sources

Comparative analysis of existing platforms for the development of vaccines against dangerous and extremely dangerous viral infections with pandemic potential

Биопрепараты: Профилактика, диагностика, лечение, 2021
The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko, T. E. Sizikova, V. N. Lebedev, S. V. Borisevich   +3 more
doaj   +4 more sources

NF-κB as an Important Factor in Optimizing Poxvirus-Based Vaccines against Viral Infections

Pathogens, 2020
Poxviruses are large dsDNA viruses that are regarded as good candidates for vaccine vectors. Because the members of the Poxviridae family encode numerous immunomodulatory proteins in their genomes, it is necessary to carry out certain modifications in ...
Justyna Struzik, Lidia Szulc-Dąbrowska
doaj   +2 more sources

Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells

Journal of Veterinary Research, 2016
Introduction: Orf virus (ORFV) is a prototype Parapoxvirus species in the Poxviridae family that causes serious zoonotic infectious disease. Goat skin fibroblast (GSF) cells are the major host targets of ORFV.
Wang Lingling, Lu Bingzhou, Zheng Haixue, Zhang Keshan, Liu Xiangtao   +4 more
doaj   +2 more sources

Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions [PDF]

Pathogens, 2020
We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy.
Laura Gallina, Federica Savini, Sabrina Canziani, Matteo Frasnelli, Antonio Lavazza, Alessandra Scagliarini, Davide Lelli   +6 more
doaj   +3 more sources

Establishment of a Challenge Model for Sheeppox Virus Infection

Microorganisms, 2020
Sheeppox virus (SPPV) together with goatpox virus and lumpy skin disease virus form the genus Capripoxvirus of the Poxviridae family. Due to their great economic importance and major impact on livelihood of small-scale farmers, OIE guidelines classify ...
Janika Wolff, Sahar Abd El Rahman, Jacqueline King, Mohamed El-Beskawy, Anne Pohlmann, Martin Beer, Bernd Hoffmann   +6 more
doaj   +2 more sources

Poxviruses in Bats … so What? [PDF]

Viruses, 2014
Poxviruses are important pathogens of man and numerous domestic and wild animal species. Cross species (including zoonotic) poxvirus infections can have drastic consequences for the recipient host.
Kate S. Baker, Pablo R. Murcia
doaj   +2 more sources

Identification of Novel Cetacean Poxviruses in Cetaceans Stranded in South West England. [PDF]

PLoS ONE, 2015
Poxvirus infections in marine mammals have been mainly reported through their clinical lesions and electron microscopy (EM). Poxvirus particles in association with such lesions have been demonstrated by EM and were previously classified as two new ...
James Barnett, Akbar Dastjerdi, Nick Davison, Rob Deaville, David Everest, Julie Peake, Christopher Finnegan, Paul Jepson, Falko Steinbach   +8 more
doaj   +3 more sources

Monkeypox: An Emerging Global Public Health Emergency

Life, 2022
The virus causing monkeypox, a rare zoonotic viral disease, belongs to the Poxviridae family and the Orthopoxvirus genus. On 23 July 2022, the World Health Organization (WHO) declared the monkeypox outbreak as a Public Health Emergency of International ...
Madhan Jeyaraman, Preethi Selvaraj, Manjunatha Budihal Halesh, Naveen Jeyaraman, Arulkumar Nallakumarasamy, Manu Gupta, Nicola Maffulli, Ashim Gupta   +7 more
doaj   +2 more sources

Innate Immune Sensing of Parapoxvirus Orf Virus and Viral Immune Evasion

Viruses
Orf virus (ORFV) is the type species of Parapoxvirus of the Poxviridae family that induces cutaneous pustular skin lesions in sheep and goats, and causes zoonotic infections in humans.
Basheer A. AlDaif, Stephen B. Fleming
doaj   +2 more sources