Results 11 to 20 of about 3,617,855 (214)

Monkeypox emerges on a global scale: A historical review and dermatologic primer

Journal of the American Academy of Dermatology, 2022
The current monkeypox outbreak reawakens the concern that poxviridae have a high potential for zoonotic spillover and causing a pandemic. Much fieldwork and research have been done by health care and public health workers in Africa during previous human ...
J. Bryer, E. Freeman, M. Rosenbach
semanticscholar   +3 more sources

Innate Immune Sensing of Parapoxvirus Orf Virus and Viral Immune Evasion

Viruses
Orf virus (ORFV) is the type species of Parapoxvirus of the Poxviridae family that induces cutaneous pustular skin lesions in sheep and goats, and causes zoonotic infections in humans.
Basheer A. AlDaif, Stephen B. Fleming
doaj   +2 more sources

Vaccinia virus modulates the redox environment by inhibiting reactive oxygen and nitrogen species with increased activity of endogenous antioxidant enzymes

Scientific Reports
The vaccinia virus (VACV) is the most studied and well-characterised member of the Poxviridae family. However, the mechanisms through which it modulates redox homeostasis in host cells remain unclear.
Marília Bueno da Silva Menegatto, Ariane Coelho Ferraz, Rafaela Lameira Souza Lima, Pedro Henrique Guimarães, Oluwashola Samuel Ola-Olu, Pedro Alves Machado-Junior, Wellington Carvalho Malta, Thaís de Fátima Silva Moraes, Frank Silva Bezerra, Breno de Mello Silva, José Carlos de Magalhães, Jordana Grazziela Alves Coelho dos Reis, Flávio Guimarães da Fonseca, Giliane de Souza Trindade, Erna Geessien Kroon, Cintia Lopes de Brito Magalhães   +15 more
doaj   +2 more sources

Monkeypox: A Global Challenge [PDF]

Liaquat National Journal of Primary Care, 2022
Monkeypox has emerged as the most significant human pathogen in recent times and is a rapidly growing threat to public health globally. Monkeypox virus is an orthopoxvirus, that belongs to the Poxviridae family.
Sannia Perwaiz Iqbal, Sajid Abbas Jaffri
doaj   +1 more source

Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics. [PDF]

Small Sci
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
N SR, Jin GW, Choy JH.
europepmc   +2 more sources

Molecular Detection and Characterization of Orf Virus in Goats With Clinical Signs From Four Districts of Tanzania. [PDF]

Vet Med Sci
ABSTRACT Background: Orf virus (ORFV), a zoonotic member of the genus Parapoxvirus, causes contagious ecthyma in sheep and goats and poses significant economic and public health concerns. Despite frequent outbreaks, molecular data on ORFV circulating in Tanzania remain scarce.
Mayenga C, Mwanandota JJ, Marisa J, Gelaye E, Misinzo G.   +4 more
europepmc   +2 more sources

Mpox (Monkeypox) in Pregnancy Updates. [PDF]

Health Sci Rep
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Dorjey Y, Chhetri DK.
europepmc   +2 more sources

[Determination of the optimal immunizing dose of heterologous goat pox virus vaccine (Poxviridae: Chordopoxvirinae: Capripoxvirus) against lumpy skin disease].

Voprosy virusologii, 2022
INTRODUCTION Lumpy skin disease (LSD), sheep pox and goat pox are dangerous diseases of domestic ruminants. Representatives of the genus of capripoxviruses are antigenically similar and can be used as a vaccine for three infections, as in the case of ...
R. Abitaev, Zh. B. Kondibaeva, Z. Amanova, Z. Sametova, A. Ussembay, Y. Bulatov   +5 more
semanticscholar   +1 more source

Milker's nodules: classic histological findings [PDF]

Anais Brasileiros de Dermatologia, 2017
: Milker's nodule is an occupational dermatovirose caused by Parapoxvirus, which is self-limited and, due to the lack of information of health professionals, may lead to underdiagnosis.
Ana Cláudia Cavalcante Espósito, Marilia Formentini Scotton Jorge, Mariângela Esther Alencar Marques, Luciana Patrícia Fernandes Abbade   +3 more
doaj   +2 more sources

[Adaptation of the sheep pox virus (Poxviridae: Capripoxvirus: Sheeppox virus) to African green monkey kidney cell line and evaluation of its immunobiological properties].

Voprosy virusologii, 2022
INTRODUCTION Outbreaks of infectious diseases seriously hinder the preservation and increase of the number of small ruminants. Such infections include sheep pox virus (SPPV).
Z. Amanova, Z. Sametova, Y. Bulatov
semanticscholar   +1 more source