Results 21 to 30 of about 5,414 (165)

Small Hero with Great Powers: Vaccinia Virus E3 Protein and Evasion of the Type I IFN Response

Biomedicines, 2022
Poxviridae have developed a plethora of strategies to evade innate and adaptive immunity. In this review, we focused on the vaccinia virus E3 protein, encoded by the E3L gene. E3 is present within the Chordopoxvirinae subfamily (with the exception of the
Mateusz Szczerba, Sambhavi Subramanian, Kelly Trainor, Megan McCaughan, Karen V. Kibler, Bertram L. Jacobs   +5 more
doaj   +2 more sources

The Re-Emergence of Mpox: Old Illness, Modern Challenges

Biomedicines
The Mpox virus (MPXV) is known to cause zoonotic disease in humans. The virus belongs to the genus Orthopoxvirus, of the family Poxviridae, and was first reported in monkeys in 1959 in Denmark and in humans in 1970 in the Congo.
Mohammad Ali Zinnah, Md Bashir Uddin, Tanjila Hasan, Shobhan Das, Fahima Khatun, Md Hasibul Hasan, Ruenruetai Udonsom, Md Masudur Rahman, Hossam M. Ashour   +8 more
doaj   +2 more sources

Exploring computational approaches to design mRNA Vaccine against vaccinia and Mpox viruses [PDF]

Immunity, Inflammation and Disease
Background Messenger RNA (mRNA) vaccines emerged as a powerful tool in the fight against infections. Unlike traditional vaccines, this unique type of vaccine elicits robust and persistent innate and humoral immune response with a unique host cell ...
Elijah K. Oladipo, Olanrewaju D. Oyelakin, Abdulsamad O. Aiyelabegan, Elizabeth O. Olajide, Victoria O. Olatayo, Kaothar P. Owolabi, Yewande B. Shittu, Rhoda O. Olugbodi, Hezekiah A. Ajala, Raji A. Rukayat, Deborah O. Olayiwola, Boluwatife A. Irewolede, Esther M. Jimah, Julius K. Oloke, Taiwo O. Ojo, Olumide F. Ajani, Bamidele A. Iwalokun, Olatunji M. Kolawole, Olumuyiwa E. Ariyo, Daniel A. Adediran, Seun E. Olufemi, Helen Onyeaka   +21 more
doaj   +2 more sources

A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB, Hanif A, Ahmad S, Shah FI, Javed B, Javed B, Iqbal S.   +6 more
europepmc   +2 more sources

Should we be concerned about treating mpox patients in orthopaedic surgery? A narrative review

Journal of Orthopaedic Reports
Background: The Mpox virus, is a zoonotic viral infection that belongs to the Orthopoxvirus genus and the poxviridae class. Infections caused by the orthopoxvirus can either be local or generalised disease.
Collen Sandile Nkosi, Yenziwe Sibongokuhle Mbambo, Lunga Gadala, Putso Learn Motubatse, Thabo Leonard Muhango   +4 more
doaj   +2 more sources

Molecular Characterisation of Orf Virus in Goats From Eastern Türkiye. [PDF]

Vet Med Sci
This study provides the molecular characterisation of Orf virus (ORFV) strains circulating in Türkiye. Phylogenetic analysis of F1L, B2L, and VIR genes reveals high genetic similarity with Asian and global isolates, highlighting the importance of multi‐gene analysis in monitoring viral outbreaks and understanding disease origins.
Özbek R, Ilgın M, Can-Şahna K.
europepmc   +2 more sources

Post-transcriptional modification of mRNA molecules in viruses of the Poxviridae family [PDF]

, 2023
Post-transcriptional modifications of mRNA molecules in viruses belonging to the Poxviridae family, including the vaccinia virus, play a key role in regulating viral gene expression and also influence virus-host cell interactions.
Jakešová, Kristýna
core   +1 more source

Mpox (Monkeypox) in Pregnancy Updates. [PDF]

Health Sci Rep
ABSTRACT Background Mpox is a zoonotic viral disease caused by the monkeypox virus, with potential for significant morbidity across all population groups, including pregnant individuals and neonates. Pregnancy represents an immunologically vulnerable state, rendering affected mothers more susceptible to severe disease progression.
Dorjey Y, Chhetri DK.
europepmc   +2 more sources

Molusco contagioso del párpado: manifestación cutánea de inmunosupresión

Infectio, 2021
Molluscum contagiosum is a cutaneous viral infection, usually benign and self-limited, caused by the molluscum contagiosum virus, of the genus Molluscipoxvirus.
Camilo Andrés Morales-Cardona
doaj   +1 more source

Global Burden of Lumpy Skin Disease, Outbreaks, and Future Challenges

Viruses, 2023
Lumpy skin disease (LSD), a current global concern, causes economic devastation in livestock industries, with cattle and water buffalo reported to have higher morbidity and lower mortality rates. LSD is caused by lumpy skin disease virus (LSDV), a member
Mahfuza Akther, Syeda Hasina Akter, Subir Sarker, Joshua W. Aleri, Henry Annandale, Sam Abraham, Jasim M. Uddin   +6 more
doaj   +1 more source