Results 11 to 20 of about 31,022 (291)
Annual Review of ImmunologyPoxviruses have evolved a wide array of mechanisms to evade the immune response, and we provide an overview of the different immunomodulatory strategies.
Bruno Hernáez, Antonio Alcamı́
semanticscholar +5 more sources
Molecular Mechanisms of Poxvirus Evolution [PDF]
mBio, 2022 Poxviruses are often thought to evolve relatively slowly because they are double-stranded DNA pathogens with proofreading polymerases. However, poxviruses have highly adaptable genomes and can undergo relatively rapid genotypic and phenotypic change, as ...
Greg Brennan +8 more
semanticscholar +6 more sources
The Evolution of Poxvirus Vaccines [PDF]
Viruses, 2015 After Edward Jenner established human vaccination over 200 years ago, attenuated poxviruses became key players to contain the deadliest virus of its own family: Variola virus (VARV), the causative agent of smallpox. Cowpox virus (CPXV) and horsepox virus
L. Sánchez-Sampedro +5 more
semanticscholar +5 more sources
The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation. [PDF]
PLoS Pathogens, 2017 The poly(A) leader at the 5'-untranslated region (5'-UTR) is an unusually striking feature of all poxvirus mRNAs transcribed after viral DNA replication (post-replicative mRNAs).
Pragyesh Dhungel +2 more
doaj +2 more sources
Decoding poxvirus genome [PDF]
Oncotarget, 2015 Citation: Yang, Z. L., & Moss, B. (2015). Decoding poxvirus genome. Oncotarget, 6(30), 28513-28514. doi:10.18632/oncotarget.5892Deciphering the information encoded in genomic sequences is a key step in modern biomedical research. Recent findings indicate
Moss, B., Yang, Zhilong L.
core +5 more sources
Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections [PDF]
Cell, 2016 Iuliia M. Gilchuk +23 more
openalex +2 more sources
Temporal expression classes and functions of vaccinia virus and mpox (monkeypox) virus genes [PDF]
mBioPoxviruses comprise pathogens that are highly pathogenic to humans and animals, causing diseases such as smallpox and mpox (formerly monkeypox). The family also contains members developed as vaccine vectors and oncolytic agents to fight other diseases ...
Yining Deng +2 more
doaj +2 more sources
mSphere, 2021 Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson +14 more
doaj +1 more source
A poxvirus ankyrin protein LSDV012 inhibits IFIT1 in a host-species-specific manner by compromising its RNA binding ability. [PDF]
PLoS PathogXie S +9 more
europepmc +3 more sources
Frontiers in Immunology, 2023 Poxvirus vectors represent versatile modalities for engineering novel vaccines and cancer immunotherapies. In addition to their oncolytic capacity and immunogenic influence, they can be readily engineered to express multiple large transgenes.
J. Whelan +26 more
semanticscholar +1 more source