Results 11 to 20 of about 14,853 (241)
Биопрепараты: Профилактика, диагностика, лечение, 2021 The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko +3 more
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Vaccines, 2023 Background: The years 2022–2023 witnessed a monkeypox virus (mpox) outbreak in some countries worldwide, where it exists in an endemic form. However, the number of infectious cases is continuously on the rise, and there has been an unexpected, drastic ...
Shiza Malik +4 more
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Viruses, 2022 Cetacean poxviruses (CePVs) cause ‘tattoo’ skin lesions in small and large cetaceans worldwide. Although the disease has been known for decades, genomic data for these poxviruses are very limited, with the exception of CePV-Tursiops aduncus, which was ...
Léa Luciani +4 more
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Cowpox Viruses: A Zoo Full of Viral Diversity and Lurking Threats
Biomolecules, 2023 Cowpox viruses (CPXVs) exhibit the broadest known host range among the Poxviridae family and have caused lethal outbreaks in various zoo animals and pets across 12 Eurasian countries, as well as an increasing number of human cases.
Ryan C. Bruneau +2 more
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Poxviruses Aren't StuPYD [PDF]
Immunity, 2005 Pathogens utilize many strategies to dampen the host inflammatory response. In this issue of Immunity, a report by Johnston and colleagues reveals a poxvirus strategy that inhibits the inflammasome, arresting secretion of interleukin-1-related cytokines, thus silencing key alarms that mobilize host defenses.
Benedict, Chris A., Ware, Carl F.
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Poxvirus Interactions with the Host Ubiquitin System
Pathogens, 2021 The ubiquitin system has emerged as a master regulator of many, if not all, cellular functions. With its large repertoire of conjugating and ligating enzymes, the ubiquitin system holds a unique mechanism to provide selectivity and specificity in ...
Sian Lant, Carlos Maluquer de Motes
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Veterinary Microbiology, 2010 (Uploaded by Plazi for the Bat Literature Project) Poxviruses compromise a group of long known important pathogens including some zoonotic members affecting lifestock animals and humans. While whole genome sequence analysis started to shed light into the molecular mechanisms underlying host cell infection, viral replication as well as virulence, our ...
Essbauer, Sandra +2 more
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Poxviral ANKR/F-box Proteins: Substrate Adapters for Ubiquitylation and More
Pathogens, 2022 Poxviruses are double-stranded DNA viruses that infect insects and a variety of vertebrate species. The large genomes of poxviruses contain numerous genes that allow these viruses to successfully establish infection, including those that help evade the ...
Robert J. Ingham +2 more
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In Silico Repurposed Drugs against Monkeypox Virus
Molecules, 2022 Monkeypox is an emerging epidemic of concern. The disease is caused by the monkeypox virus and an increasing global incidence with a 2022 outbreak that has spread to Europe amid the COVID-19 pandemic. The new outbreak is associated with novel, previously
Hilbert Yuen In Lam +2 more
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Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
, 2011 Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
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