Results 51 to 60 of about 14,853 (241)

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Dual Use Research of Concern—The Necessity of Global Bioethics Engagement

Bioethics, EarlyView.
ABSTRACT Dual use research of concern (DURC) refers to research conducted for legitimate scientific purposes that could also be misused to pose a significant threat to public health and safety, agricultural crops and other plants, animals, the environment, or national security.
Daniel J. Hurst, Christopher A. Bobier
wiley   +1 more source

Genome Variability and Gene Content in Chordopoxviruses: Dependence on Microsatellites

Viruses, 2015
To investigate gene loss in poxviruses belonging to the Chordopoxvirinae subfamily, we assessed the gene content of representative members of the subfamily, and determined whether individual genes present in each genome were intact, truncated, or ...
Eneida L. Hatcher, Chunlin Wang, Elliot J. Lefkowitz   +2 more
doaj   +1 more source

Smallpox - past or not past? [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2004
Smallpox is a potentially deadly illness caused by the variola virus, an orthopoxvirus. Severe illness followed by blister-like body rash is the sign of smallpox. Smallpox symptoms develop about 12 days after exposure. V.
Kuljić-Kapulica Nada
doaj   +1 more source

Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein [PDF]

, 1995
Two myxoma virus-rabbit hemorrhagic disease virus (RHDV) recombinant viruses were constructed with the SG33 strain of myxoma virus to protect rabbits against myxomatosis and rabbit viral hemorrhagic disease.
Bertagnoli, Stéphane, Boilletot, Eric, Boucraut-Baralon, Corine, Gelfi, Jacqueline, Laurent, Sylvie, Le Gall, Ghislaine, Milon, Alain, Petit, Frédérique, Rasschaert, Denis, Vautherot, Jean-François   +9 more
core   +2 more sources

Viruses and the cellular RNA decay machinery. [PDF]

, 2010
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core   +1 more source

The First Report of Cod Gill Poxvirus in Gills of Atlantic Cod (Gadus morhua L.) Suffering From Cardiorespiratory Disease

Journal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from
Mona C. Gjessing, Torstein Tengs, Hanne Nilsen, Saima Mohammad, Simon C. Weli   +4 more
wiley   +1 more source

Improved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors. [PDF]

, 2011
Attenuated poxviruses are safe and capable of expressing foreign antigens. Poxviruses are applied in veterinary vaccination and explored as candidate vaccines for humans.
A Alcami, A Alcami, A Harari, A Harari, A Subramanian, Abdelali Filali-Mouhim, AD Bins, AJ McNeil, Alexandre Harari, Anke Redeker, Antonio Lanzavecchia, B Perdiguero, Beatriz Perdiguero, Bertram L. Jacobs, Carmen E. Gomez, CE Gomez, CE Gomez, CE Gomez, CF Ockenhouse, CJM Melief, Clive Gray, Cornelis J. M. Melief, D Chaussabel, D Gaucher, David M. Koelle, DD Richman, DH O'Connor, DR Burton, E Paoletti, E Tryniszewska, Elias K. Haddad, Esther D. Quakkelaar, Federica Sallusto, Ferry Ossendorp, G Sutter, Giuseppe Pantaleo, GK Smith, J Tartaglia, J Tartaglia, JA Espmark, JA Symons, Jean-Philippe Goulet, Jim Tartaglia, JL Najera, JL Najera, Karen V. Kibler, L Jing, L Jing, LJ Sigal, M Carrington, M Esteban, M Terajima, Mariano Esteban, ME Perkus, ME Perkus, MJ Kuroda, MP Longhi, N Frahm, N Frahm, N Oguiura, N Romani, N van Montfoort, NA Wilson, Nikki M. Loof, OR Colamonici, P Mooij, P Mooij, PA Bart, Paul Heinen, RA Koup, Rafick P. Sékaly, RN Van Gelder, RP Sekaly, S Guerra, S McCormack, S Rerks-Ngarm, SA Migueles, SS Jackson, Stella Mayo McCaughey, Thomas Duhen, X Shen, X Wei, Y Benjamini, Z Hel, Z Hel   +84 more
core   +4 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Reindeer Parapoxvirus [PDF]

, 2012
Parapoxviruses (PPVs) are zoonotic viruses which cause contagious pustular skin infections of sheep, goats and cattle worldwide. In addition, they have more recently been shown to infect other animals such as red deer, seals, camels and reindeer ...
Hautaniemi, Maria
core   +1 more source