Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication. [PDF]
Myxoma virus (MYXV)-encoded protein M029 is a member of the poxvirus E3 family of dsRNA-binding proteins that antagonize the cellular interferon signaling pathways.
Chan, Winnie M +4 more
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Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan +14 more
wiley +1 more source
Microparasites and their potential impact on the population dynamics of small cetaceans from South America: a brief review. Document SC/59/DW8, Scientific Committee, International Whaling Commission, Anchorage, Alaska, 4-14 May 2007 [PDF]
We briefly review the pathology, epidemiology and molecular biology of cetacean viruses (including morbilli, papilloma and pox) and Brucella spp. encountered in South America.
Barrett, T. +6 more
core
The N-terminal shuttle domain of Erv1 determines the affinity for Mia40 and mediates electron transfer to the catalytic Erv1 core in yeast mitochondria [PDF]
Erv1 and Mia40 constitute the two important components of the disulfide relay system that mediates oxidative protein folding in the mitochondrial intermembrane space. Mia40 is the import receptor that recognizes the substrates introducing disulfide bonds
Aivaliotis, M. +3 more
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Highlights • Molecular characterisation of the LSDV in Algeria and Tunisia. PCR detection of the presence of the LSDV in 77.9% of the samples collected. • Cattle skin and nasal and buccal swabs were the most virulent material. • Phylogenetic analysis using the p32 gene revealed 100% sequence identity and grouping with GenBank‐published LSDV sequences ...
Ilhem Zouyed +9 more
wiley +1 more source
African swine fever virus (ASFV) belongs to the family of Asfarviridae, part of the group of nucleocytoplasmic large DNA viruses (NCLDV). Little is known about the internalization of ASFV in the host cell and the fusion membrane events that take place at
Jesús Urquiza +6 more
doaj +1 more source
A selectable and excisable marker system for the rapid creation of recombinant poxviruses. [PDF]
Genetic manipulation of poxvirus genomes through attenuation, or insertion of therapeutic genes has led to a number of vector candidates for the treatment of a variety of human diseases.
Julia L Rintoul +8 more
doaj +1 more source
Comparative biochemical and functional analysis of viral and human secreted tumor necrosis factor (TNF) decoy receptors [PDF]
© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. The blockade of tumor necrosis factor (TNF) by etanercept, a soluble version of the human TNF receptor 2 (hTNFR2), is a well established strategy to inhibit adverse TNF-mediated ...
Alcamí, Antonio +2 more
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Monkeypox has garnered significant attention following its emergence in multiple countries and its designation as a global health emergency in 2022. There is a notable deficiency in clinical and experimental data regarding pregnancy outcomes following monkeypox infection.
Jingyi Wu +3 more
wiley +1 more source
Commentary: Evidence to Guide Gun Violence Prevention in America [PDF]
Gun violence is a major threat to the public's health and safety in the United States. The articles in this volume's symposium on gun violence reveal the scope of the problem and new trends in mortality rates from gunfire.
Daniel W. Webster
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