Results 101 to 110 of about 504 (138)
Epidemiology of marine turtle fibropapillomatosis and tumour-associated chelonid alphaherpesvirus 5 (ChHV5; Scutavirus chelonidalpha5) in North-Western Mexico: a scoping review implementing the one health approach. [PDF]
Espinoza J +10 more
europepmc +1 more source
Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background. [PDF]
Alves CH +7 more
europepmc +1 more source
Epidemiology, literacy, risk factors, and clinical status of oral cancer in East Africa: A scoping review. [PDF]
Aminu K +12 more
europepmc +1 more source
Differential Effect of pp120 on Insulin Endocytosis by Two Variant Insulin Receptor Isoforms
The insulin receptor is expressed as two variably spliced isoforms that differ by the absence (isoform A) or presence (isoform B) of a 12-amino acid sequence encoded by exon 11 at the carboxy terminus of the α-subunit. Coexpression of the A isoform and pp120, a substrate of the insulin receptor tyrosine kinase, in NIH 3T3 fibroblasts increased receptor
Sonia M Najjar
exaly +4 more sources
ppl20/C-CAM, a liver plasma membrane glycoprotein, is a substrate of the insulin receptor tyrosine kinase in cell-free and intact cell systems.1, 2, 3 The cDNA encoding the rat protein was originally cloned by Lin and Guidotti4 as a Ca2+/Mg2+ ecto-ATPase. Analysis of the deduced amino acid sequence revealed that the protein is of 519 amino acids (a.a.)
Sonia M Najjar
exaly +3 more sources
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pp120, A Substrate of the Insulin Receptor Tyrosine Kinase, Is Associated With Phosphatase Activity
Biochemical and Biophysical Research Communications, 1998pp120, a plasma membrane glycoprotein, is phosphorylated on Tyr488 by the insulin receptor tyrosine kinase. This requires basal phosphorylation on Ser503 by cAMP-dependent serine kinase. Phe513, the other tyrosine residue in the intracellular domain, does not undergo insulin-stimulated phosphorylation.
Sonia M Najjar
exaly +3 more sources
Abstract Accumulating evidence indicates that the Src homology 2-containing tyrosine phosphatase 2 (SHP-2) plays an important role in signal transduction through receptor tyrosine kinase and cytokine receptors. In most models, SHP-2 appears to be a positive mediator of signaling.
Kazuhiro Nakamura, John C Cambier
openaire +2 more sources
Molecular Cloning of pp120/ ECTO-ATPase, an Endogenous Substrate of the Insulin Receptor Kinase
Advances in Experimental Medicine and Biology, 1994In recent years, a great deal of attention has been devoted to dissecting intracellular pathways of insulin action following activation of the insulin receptor kinase (1). Several laboratories have reported the identification of protein substrates of the insulin receptor tyrosine kinase (2).
Simeon I Taylor +2 more
exaly +3 more sources

