Morphological Changes of 3T3 Cells under Simulated Microgravity [PDF]
CellsBackground: Cells are sensitive to changes in gravity, especially the cytoskeletal structures that determine cell morphology. The aim of this study was to assess the effects of simulated microgravity (SMG) on 3T3 cell morphology, as demonstrated by a ...
Minh Thi Tran +13 more
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Molecular Mechanism of Malignant Transformation of Balb/c-3T3 Cells Induced by Long-Term Exposure to 1800 MHz Radiofrequency Electromagnetic Radiation (RF-EMR) [PDF]
Bioengineering, 2022 Purpose: We aimed to investigate RF-EMR-induced cell malignant transformation. Methods: We divided Balb/c-3T3 cells into sham and expo groups. The expo groups were exposed to a 1800 MHz RF continuous wave for 40 and 60 days, for 4 h per day.
Zhen Ding +3 more
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Silencing of Homeodomain-Interacting Protein Kinase 2 (HIPK2) Induces Anti-Adipogenic Effects in 3T3-L1 Adipocytes [PDF]
Current Issues in Molecular BiologyHomeodomain-interacting protein kinase 2 (HIPK2) is an important regulator of various transcription factors and cofactors, which are involved in cell growth, cell death, and embryonic development.
Anil Kumar Yadav +3 more
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Potential anti-adipogenic activity of Calligonum comosum cuminaldehyde on mouse 3T3-pre-adipocytes
Advances in Biomedical and Health Sciences, 2023 Background: Obesity is a medical condition characterized by augmented body fat mass that can adversely affect human health. Several regimens were suggested to counteract obesity and fat accumulation with limited success.
Mohammad Ghaleb Mohammad +7 more
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Comparison of Phototoxicity Sensitivity by the Neutral Red Uptake Method for BALB/c 3T3, HaCaT, and HDFa Cells In Vitro [PDF]
Innovations in Digital Health, Diagnostics, and Biomarkers, 2022 Introduction: Phototoxicity is an acute photoinduced reaction. The 3T3 neutral red uptake (NRU) phototoxicity test has high sensitivity for the determination of phototoxic substances. To further optimize the method, this study mainly focused on comparing
Qiuwen Liang, Feifei Wang, Xiao Ma
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Effects of Curcumin on Sodium Arsenite Induced Neoplastic Cell Transformation in Balb/c 3T3 Cells [PDF]
Brazilian Archives of Biology and Technology, 2021 HIGHLIGHTS Sodium arsenite can cause neoplastic transformation in cells. Curcumin reduced cell viability and increased LDH activity in transformed Balb/c 3T3 cells. Curcumin caused DNA damage in transformed Balb/c 3T3 cells.
Busra Demircioglu +4 more
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Biomolecules, 2021 GPR56 is required for the adipogenesis of preadipocytes, and the role of one of its ligands, type III collagen (ColIII), was investigated here. ColIII expression was examined by reverse transcription quantitative polymerase chain reaction, immunoblotting
Mohammad Al Hasan +4 more
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Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response. [PDF]
PLoS ONE, 2013 BACKGROUND: While pathogenic mutations in BSCL2/Seipin cause congenital generalized lipodystrophy, the underlying mechanism is largely unknown. In this study, we investigated whether and how the pathogenic missense A212P mutation of Seipin (Seipin-A212P)
Wenjie Qiu +6 more
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Prolonged induction activates Cebpα independent adipogenesis in NIH/3T3 cells. [PDF]
PLoS ONE, 2013 BACKGROUND: 3T3-L1 cells are widely used to study adipogenesis and insulin response. Their adipogenic potential decreases with time in the culture. Expressing exogenous genes in 3T3-L1 cells can be challenging.
Hsiao-Yun Shao +5 more
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Matrigel® enhances 3T3-L1 cell differentiation
Adipocyte, 2021 Culturing cells on bio-gels are believed to provide a more in vivo-like extracellular matrix. 3T3-L1 cells cultured on Matrigel® significantly alteregd their proliferation and differentiation as compared to growth on tissue culture-coated polystyrene ...
Chitmandeep Josan +2 more
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