Results 21 to 30 of about 4,897,037 (304)

Investigating the role of EPA and DHA on cellular oxidative stress; profiling antidiabetic and antihypertensive potential

open access: yesJournal of Pharmacy and Bioallied Sciences, 2022
Background: Polyunsaturated fatty acids (PUFAs) remain part of the diet and are essential for growth and development. Furthermore, omega − 3 fatty acids boost various cardiovascular disease risk factors as well as lower blood pressure and cholesterol ...
Fahad K Aldhafiri
doaj   +1 more source

Increased Oxidative Stress in Cultured 3T3-L1 Cells was Attenuated by Berberine Treatment

open access: yesNatural Product Communications, 2015
The 3T3-L1 cell line is one of the most well-characterized and reliable models for studying adipocytes. Increased oxidative stress in accumulated fat was found in 3T3-L1 cells.
Shi-Fen Dong   +5 more
doaj   +1 more source

Simple Analysis of Lipid Inhibition Activity on an Adipocyte Micro-Cell Pattern Chip

open access: yesBiomolecules, 2018
Polydimethyl-siloxane (PDMS) is often applied to fabricate cell chips. In this study, we fabricated an adipocyte microcell pattern chips using PDMS to analyze the inhibition activity of lipid droplets in mouse embryo fibroblast cells (3T3-L1) with anti ...
Gi Yong Kim   +5 more
doaj   +1 more source

Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells

open access: yesFEBS Open Bio, 2020
Dysregulation of adipocyte differentiation and dysfunction play key roles in the pathogenesis of obesity and associated disorders such as diabetes and metabolic syndrome, and as such, a better understanding of the molecular mechanism of adipogenesis may ...
Tomiyasu Murata   +7 more
doaj   +1 more source

Swainsonine inhibits proliferation and collagen synthesis of NIH-3T3 cells by declining miR-21

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Swainsonine (SW) is an indolizidine alkaloid first discovered in Swainsona canescens. This study explored the effects of SW on mouse embryo fibroblast NIH-3T3 cell proliferation and collagen synthesis, as well as potential molecule mechanisms.
Chao Li   +4 more
doaj   +1 more source

Evaluating the feasibility of Cas9 overexpression in 3T3-L1 cells for generation of genetic knock-out adipocyte cell lines

open access: yesAdipocyte, 2021
Cell lines recapitulating physiological processes can represent alternatives to animal or human studies. The 3T3-L1 cell line is used to mimic adipocyte function and differentiation. Since transfection of 3T3-L1 cells is difficult, we used a modified 3T3-
Tomás Suchý   +6 more
doaj   +1 more source

Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells

open access: yesJournal of Lipid Research, 1998
Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky   +3 more
doaj   +1 more source

High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insulin secretion in type 2 diabetes patients. This investigation was designed to determine the effects and mechanisms of HDL on glucose uptake in adipocytes ...
Qichun Zhang   +8 more
doaj   +1 more source

Assessment of Proliferation in MC-3T3-E1 cells after ES.

open access: yes, 2016
MTT assay to assess proliferation of the MC-3T3-E1 cells after ES. 100 Hz group has the highest proliferation rate at days 1, 3 compared to the other frequency and control group.
Yen Wei (1396648)   +7 more
core   +1 more source

Oleate induces apoptosis in 3T3-L1 adipocytes [PDF]

open access: yes, 2011
Oleic acid (C18:1) play an important role in proliferation of fat cells. In this study, the effect of oleate on cells viability in 3T3-L1 cells (fat cells) was investigated.
Rohana, Abu   +2 more
core   +2 more sources

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