Results 11 to 20 of about 4,897,037 (304)
Adenovirus transduction of 3T3-L1 cells [PDF]
3T3-L1 cells offer an excellent model system for studies of differentiation and biochemistry of fat cells. However, these cells are limited in their utility by the low efficiency with which DNA can be introduced by transfection.
David J. Orlicky, Jerome Schaack
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The orientation of centrioles in migrating 3T3 cells
Abstract Based on electron microscopic examination of 20 migrating 3T3 cells, the paper suggests that one centriole of a pair is preferentially oriented perpendicular, the other parallel to the substrate. The finding is interpreted as further support for the possibility that centrioles are involved in the control of migration in 3T3 cells.
G, Albrecht-Buehler, A, Bushnell
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The 89,000-Mr murine cytomegalovirus immediate-early protein stimulates c-fos expression and cellular DNA synthesis [PDF]
The immediate-early (IE) genes of murine cytomegalovirus (MCMV) are expressed in the absence of prior viral protein synthesis and regulate the transcription of MCMV early genes. The effect of MCMV IE genes on growth induction was studied.
Philipson, L. +11 more
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Background MicroRNAs (MiRNAs) are known to participate in preadipocyte differentiation, but the manner in which miR-146a-5p participates in this process remains unclear.
Yifen Wang +5 more
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The increasing prevalence of obesity has prompted intensive research into understanding its role in pathogenesis and designing appropriate treatments. To determine the signals generated from the interaction of fat cells with a target organ, a reliable ...
Noshin Mubtasim, Lauren Gollahon
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Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells
3T3-L1 cells have been used as a model to study the differentiation and physiology of adipocytes. Exogenous expression of proteins in these cells offers the prospect of understanding the protein's function(s) in adipose tissue.
David J. Orlicky +2 more
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This report describes a novel adipocyte-like cell line termed 3T3-L1/RB1 that was derived from preadipocyte cell line, 3T3-L1. The 3T3-L1/RB1 cells continued to divide after reaching confluence, formed foci, and constitutively expressed a low level of ...
Rebecca A. Baillie +3 more
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Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF. [PDF]
There is considerable interest in the ex vivo propagation of primary human basal epithelial stem/progenitor cells with a view to their use in drug development, toxicity testing and regenerative medicine.
Robert E Hynds +7 more
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Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages
Metformin, a biguanide, exerts different functions through various signaling pathways. In order to investigate the function and mechanism of metformin in burn wounds, we established burn rat models, subcutaneously injected metformin to treat the wounds ...
Liangliang Shi +9 more
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Objective The mesoderm-specific transcript (Mest) is an imprinted gene that is transcribed from the paternal allele. It is a marker of adipose tissue expansion; however, it is uncertain whether Mest expression promotes or suppresses adipogenic ...
Yoshito Kadota +3 more
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