Results 191 to 200 of about 52,072 (220)
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Integrator of PP2A and transcription
Nature Reviews Molecular Cell Biology, 2020A dual-activity complex of Integrator and protein phosphatase 2A dephosphorylates RNA polymerase II and suppresses transcription.
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Transgenic and Knockout Models of PP2A
2003Publisher Summary This chapter discusses the transgenic and knockout models of PP2A. Considering the putative role of PP2A in the pathogenesis of human diseases, the development of more transgenic and knockout models of PP2A may provide insight in the regulation of PP2A.
Götz, J, Schild, A
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PPP2R1B gene alterations inhibit interaction of PP2A-Aβ and PP2A-C proteins in colorectal cancers
Oncology Reports, 2004The chromosome region 11q is frequently deleted in colorectal cancers. The PPP2R1B tumor suppressor gene, encoding the beta isoform of the A subunit of serine/threonine-specific protein phosphatase 2A (PP2A-Abeta), located at 11q22-23, is inactivated in patients with cancer.
Masato, Tamaki +4 more
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Interactions of PP2A inhibitor proteins with PP2A regulatory subunits
2020Fosfataasit ovat tärkeitä solun sisällä tapahtuvan säätelyn kannalta. Proteiinifosfataasi 2A (PP2A) on yksi näistä säätelijöistä ja sen normaali toiminta liittyy solusyklin aktivointiin. Kun PP2A:n normaalia toimintaa häiritään, voi sen seurauksena ilmetä erilaisia sairauksia, kuten syöpää.
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Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase
Science, 2020Hai Zheng, Yilun Qi, Shibin Hu
exaly
Review for "Interaction mechanism of endogenous PP2A inhibitor protein ENSA with PP2A"
2021+4 more sources