Results 171 to 180 of about 101,448 (257)

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, EarlyView.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Endothelial Cells as Active Lipid Gatekeepers: Vascular Control of Lipid Handling and Metabolic Homeostasis. [PDF]

Nutrients
Kanda T, Urai H.
europepmc   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

Etifoxine drives macrophage M2 polarization via Schwann cell-derived progesterone activation of PPARγ to accelerate peripheral nerve repair. [PDF]

Front Cell Neurosci
Guo C, Liu S.
europepmc   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

IGF2BP3 promotes the muscle invasion of bladder cancer via PPARγ dysregulation. [PDF]

Discov Oncol
Cao JY, Peng H, Wang GY, Chang PA, Yao WT, Wang Q, Jie-Zhou, Zhang GH, Wang H, Wu JC, Li SS, Gao QL, Pei CS, Wang QC.   +13 more
europepmc   +1 more source

Fatty acid-related immune network in psoriasis: metabolic regulation of innate and adaptive immunity. [PDF]

Front Pharmacol
Wen P, Zhuo X, Xue S.
europepmc   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

A small-molecule inverse agonist of PPARγ for advanced solid tumors: a phase 1 trial. [PDF]

Nat Med
Galsky MD, Mantia C, Bowden M, Bellmunt J, Garmezy B, Iyer G, Petrylak DP, Rasco D, Gupta S, Rodriguez-Rivera I, Mikhailov Y, Joshi A, Nguyen PA, Kakrecha B, Tepper J, Costa AM, McCrone C, Rossi AP, Mertz JA, Gjini E, Meyers ML, Milowsky MI, Gao X.   +22 more
europepmc   +1 more source

A molecular approach combined with American Thyroid Association classification better stratifies recurrence risk of classic histology papillary thyroid cancer [PDF]

, 2019
Baranski, Thomas, DeWees, Todd, Grigsby, Perry, Henke, Lauren, Lin, Alexander J, Markovina, Stephanie, Pfeifer, John, Samson, Pamela, Schwarz, Julie   +8 more
core   +1 more source