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Comparative Design, In Silico Dockingand Predictive ADME/ TOX Properties of Some Novel 2, 4-hydroxy Derivatives of Thiazolidine-2, 4-diones as PPARγ Modulator

Journal of Pharmaceutical Chemistry, 2017
Peroxisome proliferated receptors (PPARs) are important targets for drugs used in the treatment of various metabolic disorders. We have reported 4-hydroxy benzylidene derivatives of thiazolidine-2,4-diones with reversed orientation in the active site of PPARγin our earlier communication.
Sabina Yasmin, Ndumiso N. Mhlongo, Mahmoud E. Soliman, Saraswathy GR, Venkatesan Jayaprakash   +4 more
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